FITC Anti-LLGL1 抗体 [4D11] (ab95802)
Key features and details
- FITC Rat monoclonal [4D11] to LLGL1
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
製品の概要
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製品名
FITC Anti-LLGL1 antibody [4D11] -
製品の詳細
FITC Rat monoclonal [4D11] to LLGL1 -
由来種
Rat -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse LLGL1. Large granular lymphocytes (LGL) enriched from C57BL/6N mouse liver
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ポジティブ・コントロール
- Mouse splenocytes.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
4D11 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95802の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 0.125-0.25µg for 105-8 cells.
Perform staining in a final volume of 100 µl. ab18446 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 0.125-0.25µg for 105-8 cells. Perform staining in a final volume of 100 µl. ab18446 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. -
組織特異性
Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease. -
配列類似性
Belongs to the WD repeat L(2)GL family.
Contains 14 WD repeats. -
翻訳後修飾
Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity). Phosphorylated at least at Ser-663 by PRKCI. -
細胞内局在
Cytoplasm > cytoskeleton. Localized to the lateral membrane during the polarization and formation cell-cell contacts. - Information by UniProt
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参照データベース
- Entrez Gene: 16897 Mouse
- SwissProt: Q80Y17 Mouse
- Unigene: 285453 Mouse
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別名
- DLG4 antibody
- DLG4, formerly antibody
- Hugl 1 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (3)
ab95802 は 3 報の論文で使用されています。
- Ortaldo JR et al. The Ly-49 family: regulation of cytotoxicity and cytokine production in murine CD3+ cells. J Immunol 160:1158-65 (1998). PubMed: 9570529
- Mason LH et al. Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2) J Exp Med 182:293-303 (1995). PubMed: 7629495
- Mason L et al. LGL-1: a non-polymorphic antigen expressed on a major population of mouse natural killer cells. J Immunol 140:4403-12 (1988). PubMed: 2453582