L-AP4, group III mGlu agonist (ab120002)
Key features and details
- Selective group III mGlu agonist
- CAS Number: 23052-81-5
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
L-AP4, group III mGlu agonist -
製品の詳細
Selective group III mGlu agonist -
生理活性の詳細
Selective group III mGlu receptor agonist.
Also available in simple stock solutions (ab144481) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS 番号
23052-81-5 -
構造式
製品の特性
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体系名
L-(+)-2-Amino-4-phosphonobutyric acid -
分子量
183.10 -
分子式
C4H10NO5P -
PubChem 登録番号
179394 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
N[C@@H](CCP(=O)(O)O)C(=O)O -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (22)
ab120002 は 22 報の論文で使用されています。
- Katada Y et al. Starburst amacrine cells amplify optogenetic visual restoration through gap junctions. Mol Ther Methods Clin Dev 30:1-13 (2023). PubMed: 37324975
- Špirková A et al. Glutamate can act as a signaling molecule in mouse preimplantation embryos†. Biol Reprod 107:916-927 (2022). PubMed: 35746896
- Ribeiro J et al. Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors. Cell Rep 35:109022 (2021). PubMed: 33882303
- Pérez-Fernández V et al. Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina. Curr Biol 29:763-774.e5 (2019). PubMed: 30799247
- Tikidji-Hamburyan A et al. Rods progressively escape saturation to drive visual responses in daylight conditions. Nat Commun 8:1813 (2017). PubMed: 29180667