Anti-Kazrin 抗体 (ab88752)
Key features and details
- Mouse polyclonal to Kazrin
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Kazrin antibody
Kazrin 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to Kazrin -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human -
免疫原
Recombinant full length protein within Human Kazrin aa 1-450. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- Rat brain tissue lysate and transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab88752の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa. |
ターゲット情報
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機能
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. -
組織特異性
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level). -
配列類似性
Belongs to the kazrin family.
Contains 3 SAM (sterile alpha motif) domains. -
細胞内局在
Cytoplasm > cytoskeleton and Cytoplasm. Cell junction > desmosome. Nucleus. Observed at the apical plasma mebrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures. - Information by UniProt
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参照データベース
- Entrez Gene: 23254 Human
- Entrez Gene: 313672 Rat
- SwissProt: Q674X7 Human
- SwissProt: Q5FWS6 Rat
- Unigene: 368823 Human
- Unigene: 3753 Rat
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別名
- HRIHFB2003 antibody
- KAZ antibody
- Kazn antibody
see all
画像
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Anti-Kazrin antibody (ab88752) at 1 µg/ml + Rat brain tissue lysate at 50ug/lane
Predicted band size: 86 kDa
Observed band size: 86 kDa
Additional bands at: 45 kDa. We are unsure as to the identity of these extra bands. -
All lanes : Anti-Kazrin antibody (ab88752) at 1 µg/ml
Lane 1 : Kazrin transfected 293T cell lysate (45.65 kDa) at 25ug/lane
Lane 2 : Non-transfected 293T cell lysate at 25ug/lane
Predicted band size: 86 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (0)
ab88752 は論文での使用が確認できていません。