Anti-KIF1C 抗体 (ab125903)
Key features and details
- Rabbit polyclonal to KIF1C
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-KIF1C antibody
KIF1C 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to KIF1C -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant fragment, corresponding to a region within amino acids 452-718 of Human KIF1C (O43896).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab125902 is purified by antigen-affinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab125903の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 123 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 123 kDa. |
ターゲット情報
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機能
Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility. -
組織特異性
Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle. -
関連疾患
Spastic ataxia 2, autosomal recessive -
配列類似性
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.
Contains 1 FHA domain.
Contains 1 kinesin motor domain. -
翻訳後修飾
Phosphorylated on tyrosine residues. -
細胞内局在
Cytoplasm, cytoskeleton. - Information by UniProt
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参照データベース
- Entrez Gene: 10749 Human
- Entrez Gene: 16562 Mouse
- Entrez Gene: 113886 Rat
- Omim: 603060 Human
- SwissProt: O43896 Human
- SwissProt: O35071 Mouse
- SwissProt: O35787 Rat
- Unigene: 435120 Human
see all -
別名
- Kif1c antibody
- KIF1C_HUMAN antibody
- Kinesin family member 1C antibody
see all
画像
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Anti-KIF1C antibody (ab125903) at 1/500 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 123 kDa5% SDS PAGE
Secondary antibody - anti-rabbit HRP (ab6721)
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab125903 は 2 報の論文で使用されています。
- Denes LT et al. Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle. Nat Commun 12:6079 (2021). PubMed: 34707124
- Dor T et al. KIF1C mutations in two families with hereditary spastic paraparesis and cerebellar dysfunction. J Med Genet 51:137-42 (2014). WB ; Human . PubMed: 24319291