JC-1, Mitochondrial membrane potential dye (ab141387)
Key features and details
- Mitochondrial membrane-potential dye
- CAS Number: 3520-43-2
- Purity: > 95%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
JC-1, Mitochondrial membrane potential dye -
製品の詳細
Mitochondrial membrane-potential dye -
精製度
> 95% -
CAS 番号
3520-43-2 -
構造式
製品の特性
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励起波長
519nm -
蛍光波長
590nm -
体系名
5,6-Dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-prop-1-enyl]-1,3-diethyl-1H-benzimidazolium iodide
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分子量
652.23 -
PubChem 登録番号
5492929 -
保存方法
Shipped at 4°C. Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 25 mM
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CCN1C2=CC(=C(C=C2[N+](=C1C=CC=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-] -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (19)
ab141387 は 19 報の論文で使用されています。
- Ding J et al. HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway. Mol Biol Rep 50:961-970 (2023). PubMed: 36376538
- Wang D et al. SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1. Cell Death Differ 30:369-382 (2023). PubMed: 36443440
- Chen F et al. Monitoring Mitochondria Function in Ferroptosis. Methods Mol Biol 2712:103-115 (2023). PubMed: 37578700
- Dong X et al. Inhibition of miR-421 Preserves Mitochondrial Function and Protects against Parkinson's Disease Pathogenesis via Pink1/Parkin-Dependent Mitophagy. Dis Markers 2022:5186252 (2022). PubMed: 35664430
- Rodríguez-Nuevo A et al. Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I. Nature 607:756-761 (2022). PubMed: 35859172