HRP Anti-Insulin + Proinsulin 抗体 [D3E7] (ab28063)
Key features and details
- HRP Mouse monoclonal [D3E7] to Insulin + Proinsulin
- Suitable for: ELISA, IHC-Fr, IHC-P, Sandwich ELISA
- Reacts with: Mouse, Rat, Cow, Human, Pig
- Conjugation: HRP
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
HRP Anti-Insulin + Proinsulin antibody [D3E7]
Insulin + Proinsulin 一次抗体 製品一覧 -
製品の詳細
HRP Mouse monoclonal [D3E7] to Insulin + Proinsulin -
由来種
Mouse -
標識
HRP -
特異性
Kd for this antibody is 6.3 x 10-8M. This antibody is specific for both insulin and proinsulin -
アプリケーション
適用あり: ELISA, IHC-Fr, IHC-P, Sandwich ELISAmore details -
種交差性
交差種: Mouse, Rat, Cow, Human, Pig -
免疫原
Human insulin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.05% Proclin 300
Constituents: 0.8% Sodium chloride, 0.02% Potassium chloride, 0.18% Dibasic monohydrogen sodium phosphate, 0.024% Monobasic dihydrogen potassium phosphate -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
D3E7 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Affibody® Molecule
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Alternative Versions
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Related Products
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sELISA pair antibody
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab28063の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA | (1) |
Use at an assay dependent concentration.
|
IHC-Fr |
Use at an assay dependent concentration.
|
|
IHC-P |
Use at an assay dependent concentration. PubMed: 24594640
|
|
Sandwich ELISA |
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [D6C4] to Insulin + Proinsulin (ab8304).
Can be used as Detection antibody with recommended pair. |
特記事項 |
---|
ELISA
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. PubMed: 24594640 |
Sandwich ELISA
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [D6C4] to Insulin + Proinsulin (ab8304). Can be used as Detection antibody with recommended pair. |
ターゲット情報
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関連性
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Defects in insulin are the cause of familial hyperproinsulinemia. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 280829 Cow
- Entrez Gene: 3630 Human
- Entrez Gene: 16333 Mouse
- Entrez Gene: 16334 Mouse
- Entrez Gene: 24505 Rat
- Omim: 176730 Human
- SwissProt: P01317 Cow
- SwissProt: P01308 Human
see all -
別名
- ILPR antibody
- ins antibody
- Insulin antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab28063 は 3 報の論文で使用されています。
- Kim J et al. 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis. Mol Cell Biol 39:N/A (2019). PubMed: 31481450
- Kim J et al. HX-1171 attenuates pancreatic ß-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model. Oncotarget 9:24260-24271 (2018). PubMed: 29849938
- Xiao F et al. Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2r?null mice. PLoS One 9:e90387 (2014). IHC-P . PubMed: 24594640