Anti-IMPACT 抗体 (ab72444)
Key features and details
- Mouse polyclonal to IMPACT
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-IMPACT antibody
IMPACT 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to IMPACT -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human -
免疫原
Full length native protein (purified), corresponding to amino acids 1-320 of Human IMPACT
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab72444の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent dilution. Predicted molecular weight: 36 kDa.
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特記事項 |
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WB
Use at an assay dependent dilution. Predicted molecular weight: 36 kDa. |
ターゲット情報
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機能
Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. -
組織特異性
Widely expressed. Expressed at high level in brain. -
配列類似性
Belongs to the IMPACT family.
Contains 1 RWD domain. - Information by UniProt
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参照データベース
- Entrez Gene: 55364 Human
- Entrez Gene: 497198 Rat
- SwissProt: Q9P2X3 Human
- SwissProt: Q5GFD9 Rat
- Unigene: 515317 Human
- Unigene: 190651 Rat
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別名
- IMPACT antibody
- Impact homolog (mouse) antibody
- Impact homolog antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab72444 は 1 報の論文で使用されています。
- Habibi D et al. High expression of IMPACT protein promotes resistance to indoleamine 2,3-dioxygenase-induced cell death. J Cell Physiol 225:196-205 (2010). WB ; Human . PubMed: 20648630