Anti-IL-20R2 抗体 (ab124332)
Key features and details
- Rabbit polyclonal to IL-20R2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-20R2 antibody
IL-20R2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IL-20R2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Human IL-20R2 aa 30-231.
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ポジティブ・コントロール
- Human fetal testis tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute in 200µl sterile H2O. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab124332の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/100 - 1/500.
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特記事項 |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. -
組織特異性
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. -
配列類似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 53833 Human
- Entrez Gene: 213208 Mouse
- Entrez Gene: 501043 Rat
- Omim: 605621 Human
- SwissProt: Q6UXL0 Human
- Unigene: 61232 Human
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別名
- DIRS1 antibody
- Fibronectin type III domain containing 6 antibody
- FNDC6 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab124332 は 4 報の論文で使用されています。
- Ónody A et al. Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases. J Transl Med 19:237 (2021). PubMed: 34078403
- Pap D et al. Characterization of IL-19, -20, and -24 in acute and chronic kidney diseases reveals a pro-fibrotic role of IL-24. J Transl Med 18:172 (2020). PubMed: 32306980
- An W et al. Exogenous IL-19 attenuates acute ischaemic injury and improves survival in male mice with myocardial infarction. Br J Pharmacol N/A:N/A (2018). PubMed: 30460984
- Steinert A et al. The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models. J Immunol 199:2570-2584 (2017). PubMed: 28864472