Anti-IL-10RB/IL-10R2 抗体 (ab106282)
Key features and details
- Rabbit polyclonal to IL-10RB/IL-10R2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-10RB/IL-10R2 antibody
IL-10RB/IL-10R2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IL-10RB/IL-10R2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- Human fetal heart, liver, kidney and muscle lysates
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200ul distilled H2O. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106282の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use at an assay dependent concentration.
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WB |
1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
WB
1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). |
ターゲット情報
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機能
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. -
関連疾患
Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) [MIM:612567]. It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. -
配列類似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3588 Human
- Entrez Gene: 16155 Mouse
- Entrez Gene: 304091 Rat
- Omim: 123889 Human
- SwissProt: Q08334 Human
- SwissProt: Q61190 Mouse
- Unigene: 654593 Human
- Unigene: 4154 Mouse
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別名
- Cd210 antibody
- CDw210b antibody
- CRF2 4 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab106282 は 1 報の論文で使用されています。
- Reemann P et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). PubMed: 24284923