Anti-ID2 抗体 [2457C5a] (ab53545)
Key features and details
- Mouse monoclonal [2457C5a] to ID2
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
製品の概要
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製品名
Anti-ID2 antibody [2457C5a]
ID2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2457C5a] to ID2 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Recombinant human ID2
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.0225% Potassium chloride, PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
ab53545 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane. -
ポリ/モノ
モノクローナル -
クローン名
2457C5a -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53545の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
Use at an assay dependent concentration. Detects a band of approximately 32 kDa (predicted molecular weight: 15 kDa).
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特記事項 |
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WB
Use at an assay dependent concentration. Detects a band of approximately 32 kDa (predicted molecular weight: 15 kDa). |
ターゲット情報
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機能
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression. -
組織特異性
Highly expressed in early fetal tissues, including those of the central nervous system. -
配列類似性
Contains 1 basic helix-loop-helix (bHLH) domain. -
発生段階
Found in most early fetal tissues but not in the corresponding mature tissues. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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別名
- bHLHb26 antibody
- Cell growth inhibiting gene 8 antibody
- class B basic helix loop helix protein 26 antibody
see all
画像
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Anti-ID2 antibody [2457C5a] (ab53545) + immunised recombinant protein
Predicted band size: 15 kDa
Observed band size: 32 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (1)
ab53545 は 1 報の論文で使用されています。
- Cao Y et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun 10:1280 (2019). PubMed: 30894532