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ab8580 has been referenced in 226 publications.
- Sauer S et al. T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. Proc Natl Acad Sci U S A : (2008).
ChIP;
Fruit fly (Drosophila melanogaster).
PubMed: 18509048
- Roh TY et al. The genomic landscape of histone modifications in human T cells. Proc Natl Acad Sci U S A 103:15782-7 (2006).
ChIP;
Human.
PubMed: 17043231
- Kwon T et al. Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. EMBO J 22:292-303 (2003).
PubMed: 12514135
- Santos-Rosa H et al. Active genes are tri-methylated at K4 of histone H3. Nature 419:407-11 (2002).
PubMed: 12353038
- Wu MF et al. SWI2/SNF2 chromatin remodeling ATPases overcome polycomb repression and control floral organ identity with the LEAFY and SEPALLATA3 transcription factors. Proc Natl Acad Sci U S A 109:3576-81 (2012).
ChIP.
PubMed: 22323601
- Youn MY et al. JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation. J Biol Chem 287:12994-3004 (2012).
ICC/IF;
Human.
PubMed: 22375008
- Wu SF et al. Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Res 21:578-89 (2011).
WB;
Zebrafish.
PubMed: 21383318
- Liu Y et al. Ab initio identification of transcription start sites in the Rhesus macaque genome by histone modification and RNA-Seq. Nucleic Acids Res 39:1408-18 (2011).
CHIPseq;
Macaque Monkey.
PubMed: 20952408
- Tozawa H et al. Genome-Wide Approaches Reveal Functional Interleukin-4-Inducible STAT6 Binding to the Vascular Cell Adhesion Molecule 1 Promoter. Mol Cell Biol 31:2196-209 (2011).
PubMed: 21464207
- Valenzuela MS et al. Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences. PLoS One 6:e17308 (2011).
ChIP;
Human.
PubMed: 21602917
- Vernimmen D et al. Polycomb eviction as a new distant enhancer function. Genes Dev 25:1583-8 (2011).
ChIP;
Mouse.
PubMed: 21828268
- Stevens JR et al. FACT, the Bur Kinase Pathway, and the Histone Co-Repressor HirC Have Overlapping Nucleosome-Related Roles in Yeast Transcription Elongation. PLoS One 6:e25644 (2011).
WB;
Saccharomyces cerevisiae.
PubMed: 22022426
- Szulwach KE et al. Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J Cell Biol 189:127-41 (2010).
PubMed: 20368621
- Hajji N et al. Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. Oncogene : (2010).
WB;
Human.
PubMed: 20118981
- Maass PG et al. A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E. Hum Mol Genet 19:848-60 (2010).
ChIP;
Human.
PubMed: 20015959
- Dahl JA et al. Histone h3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos. PLoS One 5:e9150 (2010).
ChIP;
Mouse.
PubMed: 20161773
- Tao Y et al. Lsh Mediated RNA Polymerase II Stalling at HoxC6 and HoxC8 Involves DNA Methylation. PLoS One 5:e9163 (2010).
WB;
Mouse.
PubMed: 20161795
- Obier N & Müller AM Chromatin flow cytometry identifies changes in epigenetic cell states. Cells Tissues Organs 191:167-74 (2010).
Flow Cyt;
Mouse.
PubMed: 19776550
- Sun J & Li R Human negative elongation factor activates transcription and regulates alternative transcription initiation. J Biol Chem 285:6443-52 (2010).
ChIP;
Human.
PubMed: 20028984
- Rodriguez C et al. CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus. Biochem Biophys Res Commun 392:129-34 (2010).
ChIP.
PubMed: 20051228
- Pedrosa E et al. ChIP-chip analysis of neurexins and other candidate genes for addiction and neuropsychiatric disorders. J Neurogenet 24:5-17 (2010).
PubMed: 19968605
- Agarwal S et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature 464:292-6 (2010).
ChIP;
Human.
PubMed: 20164838
- Coolen MW et al. Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity. Nat Cell Biol 12:235-46 (2010).
ChIP;
Human.
PubMed: 20173741
- Lu TY et al. Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells. J Biol Chem 285:8719-32 (2010).
ChIP;
Human.
PubMed: 20064925
- Wen H et al. Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation. J Biol Chem 285:9322-6 (2010).
ICC/IF;
Human.
PubMed: 20129925
- Ribarska T et al. Epigenetic inactivation of the placentally imprinted tumor suppressor gene TFPI2 in prostate carcinoma. Cancer Genomics Proteomics 7:51-60 (2010).
ChIP;
Human.
PubMed: 20335518
- Goldberg AD et al. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140:678-91 (2010).
PubMed: 20211137
- Ceru S et al. Stefin B interacts with histones and cathepsin L in the nucleus. J Biol Chem 285:10078-86 (2010).
WB;
Human.
PubMed: 20075068
- Ghisletti S et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32:317-28 (2010).
ChIP;
Mouse.
PubMed: 20206554
- Chia DJ et al. Distinct alterations in chromatin organization of the two IGF-I promoters precede growth hormone-induced activation of IGF-I gene transcription. Mol Endocrinol 24:779-89 (2010).
ChIP;
Rat.
PubMed: 20160126
- Seenundun S et al. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J 29:1401-11 (2010).
ChIP;
Mouse.
PubMed: 20300060
- Yu J et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 17:443-54 (2010).
ChIP;
Human.
PubMed: 20478527
- Liu C et al. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 6:433-44 (2010).
ChIP;
Mouse.
PubMed: 20452318
- Panicker LM et al. Nuclear localization of the G protein beta5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein. J Neurochem : (2010).
WB;
Mouse.
PubMed: 20100282
- Horáková AH et al. SUV39h-independent association of HP1 beta with fibrillarin-positive nucleolar regions. Chromosoma 119:227-41 (2010).
WB, ChIP;
Mouse.
PubMed: 20033197
- Aiden AP et al. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell 6:591-602 (2010).
ChIP;
Human.
PubMed: 20569696
- Lengner CJ et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141:872-83 (2010).
ChIP;
Human.
PubMed: 20471072
- Kanhere A et al. Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2. Mol Cell 38:675-88 (2010).
PubMed: 20542000
- Earley KW et al. Mechanisms of HDA6-mediated rRNA gene silencing: suppression of intergenic Pol II transcription and differential effects on maintenance versus siRNA-directed cytosine methylation. Genes Dev 24:1119-32 (2010).
ChIP.
PubMed: 20516197
- Gerlitz G & Bustin M Efficient cell migration requires global chromatin condensation. J Cell Sci 123:2207-17 (2010).
ICC/IF;
Mouse.
PubMed: 20530575
- Muntean AG et al. The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis. Cancer Cell 17:609-21 (2010).
PubMed: 20541477
- Gómez-Cabello D et al. Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1. Cancer Res 70:1866-74 (2010).
ChIP;
Mouse.
PubMed: 20179197
- Chen LT et al. Involvement of Arabidopsis histone deacetylase HDA6 in ABA and salt stress response. J Exp Bot 61:3345-53 (2010).
ChIP;
Arabidopsis thaliana.
PubMed: 20519338
- Lui JC et al. Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth. FASEB J 24:3083-92 (2010).
ChIP/Chip;
Mouse.
PubMed: 20371622
- Binda O et al. Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics 5:767-75 (2010).
PubMed: 21124070
- Cao F et al. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. PLoS One 5:e14102 (2010).
WB.
PubMed: 21124902
- Dreijerink KM et al. The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation. Mol Cell Biol 29:5060-9 (2009).
PubMed: 19596783
- Steiner LA et al. Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes. Mol Cell Biol 29:5399-412 (2009).
ChIP/Chip;
Human.
PubMed: 19687298
- Wang P et al. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol 29:6074-85 (2009).
ChIP/Chip;
Mouse.
PubMed: 19703992
- Kim D et al. The role of PTIP in maintaining embryonic stem cell pluripotency. Stem Cells 27:1516-23 (2009).
WB;
Mouse.
PubMed: 19544464
- Miranda TB et al. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther 8:1579-88 (2009).
ChIP;
Human.
PubMed: 19509260
- Pedrosa E et al. Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip). J Neurogenet 23:341-52 (2009).
ChIP/Chip.
PubMed: 19225952
- Liu Y et al. Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex. Mol Cell Biol 29:4852-63 (2009).
ChIP.
PubMed: 19581288
- Shibuya K et al. RNA-directed DNA methylation induces transcriptional activation in plants. Proc Natl Acad Sci U S A 106:1660-5 (2009).
ChIP;
Plants.
PubMed: 19164525
- Naito M et al. Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene. Am J Pathol 174:54-62 (2009).
ChIP;
Mouse.
PubMed: 19095962
- Feng B et al. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb. Nat Cell Biol 11:197-203 (2009).
ChIP.
PubMed: 19136965
- Gargiulo G et al. NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation. Dev Cell 16:466-81 (2009).
ChIP.
PubMed: 19289091
- Schmitz RJ et al. Histone H2B deubiquitination is required for transcriptional activation of FLOWERING LOCUS C and for proper control of flowering in Arabidopsis. Plant Physiol 149:1196-204 (2009).
WB;
Arabidopsis thaliana.
PubMed: 19091875
- Kim JH et al. Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res 19:533-44 (2009).
PubMed: 19141594
- Locatelli S et al. Chromatin and DNA Modifications in the Opaque2-Mediated Regulation of Gene Transcription during Maize Endosperm Development. Plant Cell : (2009).
PubMed: 19482970
- Hurd PJ et al. Phosphorylation of histone H3 Thr-45 is linked to apoptosis. J Biol Chem 284:16575-83 (2009).
WB;
Human.
PubMed: 19363025
- Hammoud SS et al. Distinctive chromatin in human sperm packages genes for embryo development. Nature 460:473-8 (2009).
ChIP;
Human.
PubMed: 19525931
- Mravinac B et al. Histone modifications within the human X centromere region. PLoS One 4:e6602 (2009).
ChIP;
Human.
PubMed: 19672304
- Makkonen H et al. Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers. Nucleic Acids Res 37:4135-48 (2009).
ChIP.
PubMed: 19433513
- Caslini C et al. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol 29:4519-26 (2009).
PubMed: 19528237
- Pandorf CE et al. Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading. Am J Physiol Cell Physiol 297:C6-16 (2009).
ChIP.
PubMed: 19369448
- Egloff S et al. Chromatin structure is implicated in "late" elongation checkpoints on the U2 snRNA and beta-actin genes. Mol Cell Biol 29:4002-13 (2009).
ChIP;
Human.
PubMed: 19451231
- Tamada Y et al. ARABIDOPSIS TRITHORAX-RELATED7 is required for methylation of lysine 4 of histone H3 and for transcriptional activation of FLOWERING LOCUS C. Plant Cell 21:3257-69 (2009).
PubMed: 19855050
- Li C et al. Regulation of oleosin expression in developing peanut (Arachis hypogaea L.) embryos through nucleosome loss and histone modifications. J Exp Bot 60:4371-82 (2009).
PubMed: 19737778
- Jacinto FV et al. Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. Oncogene 28:4212-24 (2009).
ChIP;
Human.
PubMed: 19734945
- Lee JH & Skalnik DG Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes. Mol Cell Biol 28:609-18 (2008).
ChIP;
Human.
PubMed: 17998332
- Casas-Mollano JA et al. The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas. Proc Natl Acad Sci U S A 105:6486-91 (2008).
WB, ChIP;
Chlamydomonas reinhardtii.
PubMed: 18420823
- Akimzhanov A et al. Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling. Am J Pathol 172:215-24 (2008).
ChIP;
Human.
PubMed: 18156209
- Casas-Mollano JA et al. Diversification of the core RNA interference machinery in Chlamydomonas reinhardtii and the role of DCL1 in transposon silencing. Genetics 179:69-81 (2008).
PubMed: 18493041
- Walter K et al. Stem cell specific epigenetic priming and B cell specific transcriptional activation at the mouse Cd19 locus. Blood : (2008).
PubMed: 18552207
- Ceribelli M et al. The histone-like NF-Y is a bifunctional transcription factor. Mol Cell Biol 28:2047-58 (2008).
ChIP.
PubMed: 18212061
- Meissner A et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature : (2008).
ChIP;
Mouse.
PubMed: 18600261
- Corry GN et al. Subnuclear localization and mobility are key indicators of PAX3 dysfunction in Waardenburg syndrome. Hum Mol Genet 17:1825-37 (2008).
PubMed: 18325909
- Schotta G et al. A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev 22:2048-61 (2008).
ChIP;
Mouse.
PubMed: 18676810
- Seneda MM et al. Developmental regulation of histone H3 methylation at lysine 4 in the porcine ovary. Reproduction 135:829-38 (2008).
IHC-P;
Pig.
PubMed: 18502896
- Lopez-Bigas N et al. Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation. Mol Cell 31:520-30 (2008).
PubMed: 18722178
- Chou SD & Tomasi TB Spatial distribution of histone methylation during MHC class II expression. Mol Immunol 45:971-80 (2008).
PubMed: 17850872
- Shema E et al. The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes Dev 22:2664-76 (2008).
ChIP/Chip;
Human.
PubMed: 18832071
- Dutta D et al. Activation of the VEGFR1 chromatin domain: an angiogenic signal-ETS1/HIF-2alpha regulatory axis. J Biol Chem 283:25404-13 (2008).
ChIP;
Human.
PubMed: 18625704
- Taylor JM et al. Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements. Nucleic Acids Res 36:4845-62 (2008).
ChIP;
Human.
PubMed: 18653526
- Chowdhury M et al. Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus. Proc Natl Acad Sci U S A 105:15872-7 (2008).
ChIP;
Human.
PubMed: 18836073
- Oh S et al. Genic and global functions for Paf1C in chromatin modification and gene expression in Arabidopsis. PLoS Genet 4:e1000077 (2008).
ChIP;
Arabidopsis thaliana.
PubMed: 18725930
- Duncan EM et al. Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell 135:284-94 (2008).
WB;
Mouse.
PubMed: 18957203
- Lim CY et al. Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages. Cell Stem Cell 3:543-54 (2008).
ChIP;
Mouse.
PubMed: 18804426
- Lagarou A et al. dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing. Genes Dev 22:2799-810 (2008).
WB;
Fruit fly (Drosophila melanogaster).
PubMed: 18923078
- Vitaliano-Prunier A et al. Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation. Nat Cell Biol 10:1365-71 (2008).
WB;
Saccharomyces cerevisiae.
PubMed: 18849979
- Zhu ED et al. Wdr5 is essential for osteoblast differentiation. J Biol Chem 283:7361-7 (2008).
WB;
Mouse.
PubMed: 18201971
- Lloret-Llinares M et al. Characterization of Drosophila melanogaster JmjC+N histone demethylases. Nucleic Acids Res : (2008).
ICC/IF;
Fruit fly (Drosophila melanogaster).
PubMed: 18375980
- Dahl JA & Collas P MicroChIP--a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies. Nucleic Acids Res 36:e15 (2008).
ChIP;
Human.
PubMed: 18202078
- Ekici M et al. Transcription of Genes Encoding Synaptic Vesicle Proteins in Human Neural Stem Cells: CHROMATIN ACCESSIBILITY, HISTONE METHYLATION PATTERN, AND THE ESSENTIAL ROLE OF REST. J Biol Chem 283:9257-68 (2008).
ChIP;
Human.
PubMed: 18234667
- Smith AE et al. Heritable Gene Repression through the Action of a Directed DNA Methyltransferase at a Chromosomal Locus. J Biol Chem 283:9878-85 (2008).
ChIP;
Mouse.
PubMed: 18272522
- Respuela P et al. Histone acetylation and methylation at sites initiating divergent polycistronic transcription in trypanosoma cruzi. J Biol Chem : (2008).
ChIP;
Tetrahymena sp., Trypanosoma cruzi.
PubMed: 18400752
- Dunican DS et al. xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development 135:1295-302 (2008).
WB.
PubMed: 18305009
- Lupien M et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132:958-70 (2008).
ChIP;
Human.
PubMed: 18358809
- Williams A et al. Position effect variegation and imprinting of transgenes in lymphocytes. Nucleic Acids Res 36:2320-9 (2008).
ChIP;
Mouse.
PubMed: 18296483
- Donati G et al. An NF-Y-dependent switch of positive and negative histone methyl marks on CCAAT promoters. PLoS ONE 3:e2066 (2008).
ChIP;
Human.
PubMed: 18446193
- Bonnefoy E et al. The essential role of Drosophila HIRA for de novo assembly of paternal chromatin at fertilization. PLoS Genet 3:1991-2006 (2007).
IHC-Fr;
Fruit fly (Drosophila melanogaster).
PubMed: 17967064
- Klose RJ et al. The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128:889-900 (2007).
WB.
PubMed: 17320163
- Demers C et al. Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus. Mol Cell 27:573-84 (2007).
ChIP;
Mouse.
PubMed: 17707229
- Altaf M et al. Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin. Mol Cell 28:1002-14 (2007).
WB;
Saccharomyces cerevisiae.
PubMed: 18158898
- Kinyamu HK & Archer TK Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription. Mol Cell Biol 27:4891-904 (2007).
WB;
Human.
PubMed: 17438138
- Attema JL et al. Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis. Proc Natl Acad Sci U S A 104:12371-6 (2007).
ChIP.
PubMed: 17640913
- Liu C et al. Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism. Nature 447:477-81 (2007).
PubMed: 17476214
- Kirmizis A et al. Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature 449:928-32 (2007).
WB;
Saccharomyces cerevisiae.
PubMed: 17898715
- Guccione E et al. Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive. Nature 449:933-7 (2007).
ChIP;
Human.
PubMed: 17898714
- Chang B et al. JMJD6 is a histone arginine demethylase. Science 318:444-7 (2007).
WB, ICC/IF;
Human.
PubMed: 17947579
- Vaquero A et al. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 450:440-4 (2007).
ICC/IF;
Mouse.
PubMed: 18004385
- De Santa F et al. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 130:1083-94 (2007).
WB, ChIP;
Human.
PubMed: 17825402
- Andersen EC & Horvitz HR Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Development 134:2991-9 (2007).
WB;
Caenorhabditis elegans.
PubMed: 17634190
- Yokoyama R et al. A plasmid model system shows that Drosophila dosage compensation depends on the global acetylation of histone H4 at lysine 16 and is not affected by depletion of common transcription elongation chromatin marks. Mol Cell Biol 27:7865-70 (2007).
PubMed: 17875941
- Hoogenkamp M et al. The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis. Mol Cell Biol 27:7425-38 (2007).
PubMed: 17785440
- Aguilera O et al. The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. Carcinogenesis 28:1877-84 (2007).
PubMed: 17449905
- Schnekenburger M et al. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol Cell Biol 27:7089-101 (2007).
ChIP;
Mouse.
PubMed: 17682057
- Sarcinella E et al. Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. Mol Cell Biol 27:6457-68 (2007).
WB;
Human.
PubMed: 17636032
- Sullivan KE et al. Epigenetic regulation of tumor necrosis factor alpha. Mol Cell Biol 27:5147-60 (2007).
ChIP;
Human.
PubMed: 17515611
- Wöhrle S et al. Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Mol Cell Biol 27:8164-77 (2007).
PubMed: 17923689
- Yagi R et al. Regulation of the Il4 gene is independently controlled by proximal and distal 3' enhancers in mast cells and basophils. Mol Cell Biol 27:8087-97 (2007).
PubMed: 17908791
- Godmann M et al. Dynamic regulation of histone H3 methylation at lysine 4 in mammalian spermatogenesis. Biol Reprod 77:754-64 (2007).
IHC-P;
Mouse.
PubMed: 17634443
- Barski A et al. High-resolution profiling of histone methylations in the human genome. Cell 129:823-37 (2007).
PubMed: 17512414
- Brinkman AB et al. DNA methylation immediately adjacent to active histone marking does not silence transcription. Nucleic Acids Res 35:801-11 (2007).
PubMed: 17202157
- Freberg CT et al. Epigenetic Reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract. Mol Biol Cell 18:1543-53 (2007).
PubMed: 17314394
- Dahl JA & Collas P Q2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells. Stem Cells 25:1037-46 (2007).
PubMed: 17272500
- Villa R et al. Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell 11:513-25 (2007).
PubMed: 17560333
- Rathke C et al. Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila. J Cell Sci 120:1689-700 (2007).
PubMed: 17452629
- Tesar PJ et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448:196-9 (2007).
PubMed: 17597760
- Tavner F et al. Targeting an E2F site in the mouse genome prevents promoter silencing in quiescent and post-mitotic cells. Oncogene 26:2727-35 (2007).
PubMed: 17072340
- Lubitz S et al. Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2. Mol Biol Cell 18:2356-66 (2007).
PubMed: 17429066
- Yee LF et al. Ectopic expression of HCMV IE72 and IE86 proteins is sufficient to induce early gene expression but not production of infectious virus in undifferentiated promonocytic THP-1 cells. Virology 363:174-88 (2007).
PubMed: 17331553
- Rybtsova N et al. Transcription-coupled deposition of histone modifications during MHC class II gene activation. Nucleic Acids Res 35:3431-41 (2007).
PubMed: 17478518
- Chen L et al. Widespread, exceptionally high levels of histone H3 lysine 4 trimethylation largely mediate "privileged" gene expression. Gene Expr 13:271-82 (2007).
PubMed: 17605300
- Mikkelsen TS et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448:553-60 (2007).
PubMed: 17603471
- Guenther MG et al. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130:77-88 (2007).
ChIP/Chip;
Human.
PubMed: 17632057
- Tanaka T et al. hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes. Cell 130:638-50 (2007).
ChIP;
Human.
PubMed: 17719542
- Vermeulen M et al. Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 131:58-69 (2007).
WB;
Human.
PubMed: 17884155
- Krejcí A & Bray S Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers. Genes Dev 21:1322-7 (2007).
ChIP;
Fruit fly (Drosophila melanogaster).
PubMed: 17545467
- Hayakawa T et al. RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation. Genes Cells 12:811-26 (2007).
WB;
Human.
PubMed: 17573780
- Koch CM et al. The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res 17:691-707 (2007).
ChIP/Chip;
Human.
PubMed: 17567990
- Taverna SD et al. Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A 104:2086-91 (2007).
WB;
Tetrahymena sp..
PubMed: 17284592
- Bracken AP et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Genes Dev 21:525-30 (2007).
ChIP;
Human.
PubMed: 17344414
- Krysinska H et al. A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol 27:878-87 (2007).
ChIP;
Mouse.
PubMed: 17116688
- Chow JC et al. Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible. Proc Natl Acad Sci U S A 104:10104-9 (2007).
ChIP;
Human.
PubMed: 17537922
- Rangwala SH & Richards EJ Differential epigenetic regulation within an Arabidopsis retroposon family. Genetics 176:151-60 (2007).
ChIP;
Arabidopsis thaliana.
PubMed: 17339215
- Hattori N et al. Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. Genes Cells 12:387-96 (2007).
ChIP;
Mouse.
PubMed: 17352742
- Lujambio A et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 67:1424-9 (2007).
PubMed: 17308079
- Cooper SJ et al. Serum response factor binding sites differ in three human cell types. Genome Res 17:136-44 (2007).
ChIP;
Human.
PubMed: 17200232
- Abarrategui I & Krangel MS Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination. EMBO J 26:4380-90 (2007).
ChIP;
Mouse.
PubMed: 17882258
- Denissov S et al. Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J 26:944-54 (2007).
Human.
PubMed: 17268553
- Agger K et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449:731-4 (2007).
WB, ChIP;
Mouse.
PubMed: 17713478
- Pickersgill H et al. Characterization of the Drosophila melanogaster genome at the nuclear lamina. Nat Genet 38:1005-14 (2006).
PubMed: 16878134
- Earley K et al. Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance. Genes Dev 20:1283-93 (2006).
PubMed: 16648464
- Caslini C et al. Histone modifications silence the GATA transcription factor genes in ovarian cancer. Oncogene 25:5446-61 (2006).
PubMed: 16607277
- Calzari L et al. The histone deubiquitinating enzyme Ubp10 is involved in rDNA locus control in Saccharomyces cerevisiae by affecting Sir2p association. Genetics 174:2249-54 (2006).
PubMed: 17028327
- Nelson JD et al. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 1:179-85 (2006).
PubMed: 17406230
- Guccione E et al. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol 8:764-70 (2006).
PubMed: 16767079
- Mueller JE et al. The requirements for COMPASS and Paf1 in transcriptional silencing and methylation of histone H3 in Saccharomyces cerevisiae. Genetics 173:557-67 (2006).
PubMed: 16582434
- Tripic T et al. The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochem Biophys Res Commun 339:905-14 (2006).
PubMed: 16329992
- Dou Y et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol 13:713-9 (2006).
PubMed: 16878130
- Raman SB et al. Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis. Mol Microbiol 60:697-709 (2006).
PubMed: 16629671
- Dreijerink KM et al. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer Res 66:4929-35 (2006).
PubMed: 16651450
- Li C et al. Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer. Mol Biol Cell 17:3848-59 (2006).
PubMed: 16807355
- Takeda S et al. Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. Genes Dev 20:2397-409 (2006).
PubMed: 16951254
- Azuara V et al. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8:532-8 (2006).
PubMed: 16570078
- Lemasson I et al. Tax-dependent displacement of nucleosomes during transcriptional activation of human T-cell leukemia virus type 1. J Biol Chem 281:13075-82 (2006).
PubMed: 16547351
- Yamane K et al. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 125:483-95 (2006).
PubMed: 16603237
- Donati G et al. Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters. Nucleic Acids Res 34:3116-27 (2006).
ChIP;
Human.
PubMed: 16757577
- Tsumura A et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11:805-14 (2006).
PubMed: 16824199
- Huettel B et al. Endogenous targets of RNA-directed DNA methylation and Pol IV in Arabidopsis. EMBO J 25:2828-36 (2006).
PubMed: 16724114
- Yan C & Boyd DD Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression. Mol Cell Biol 26:6357-71 (2006).
ChIP.
PubMed: 16914722
- Lis ET & Romesberg FE Role of Doa1 in the Saccharomyces cerevisiae DNA damage response. Mol Cell Biol 26:4122-33 (2006).
WB;
Saccharomyces cerevisiae.
PubMed: 16705165
- de Bruijn DR et al. The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation. Cancer Res 66:9474-82 (2006).
ChIP;
Human.
PubMed: 17018603
- Wardle FC et al. Zebrafish promoter microarrays identify actively transcribed embryonic genes. Genome Biol 7:R71 (2006).
ChIP;
Zebrafish.
PubMed: 16889661
- Valls E et al. Role of histone modifications in marking and activating genes through mitosis. J Biol Chem 280:42592-600 (2005).
ICC/IF, ChIP;
Human.
PubMed: 16199528
- Nguyen TT et al. Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene. Mol Cell Biol 25:2147-57 (2005).
ChIP;
Mouse.
PubMed: 15743813
- Im H et al. Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region. Proc Natl Acad Sci U S A 102:17065-70 (2005).
ChIP;
Human.
PubMed: 16286657
- Chan GC et al. Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. J Immunol 175:3846-61 (2005).
ChIP;
Human.
PubMed: 16148131
- Chalkiadaki A & Talianidis I SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin. Mol Cell Biol 25:5095-105 (2005).
ChIP;
Human.
PubMed: 15923626
- Schlichter A & Cairns BR Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. EMBO J 24:1222-31 (2005).
PubMed: 15775977
- Milne TA et al. MLL associates specifically with a subset of transcriptionally active target genes. Proc Natl Acad Sci U S A 102:14765-70 (2005).
PubMed: 16199523
- Farris SD et al. Transcription-induced chromatin remodeling at the c-myc gene involves the local exchange of histone H2A.Z. J Biol Chem 280:25298-303 (2005).
PubMed: 15878876
- Lee JH & Skalnik DG CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem 280:41725-31 (2005).
PubMed: 16253997
- Ballas N et al. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121:645-57 (2005).
PubMed: 15907476
- Cho DH et al. Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. Mol Cell 20:483-9 (2005).
PubMed: 16285929
- Emre NC et al. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Mol Cell 17:585-94 (2005).
PubMed: 15721261
- Bernstein BE et al. Genomic maps and comparative analysis of histone modifications in human and mouse. Cell 120:169-81 (2005).
PubMed: 15680324
- Carrozza MJ et al. Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123:581-92 (2005).
PubMed: 16286007
- Spada F et al. Plasticity of histone modifications across the invertebrate to vertebrate transition: histone H3 lysine 4 trimethylation in heterochromatin. Chromosome Res 13:57-72 (2005).
PubMed: 15861294
- Pokholok DK et al. Genome-wide map of nucleosome acetylation and methylation in yeast. Cell 122:517-27 (2005).
PubMed: 16122420
- Ozdemir A et al. Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae. J Biol Chem 280:25949-52 (2005).
PubMed: 15888442
- Lefevre P et al. Differentiation-dependent alterations in histone methylation and chromatin architecture at the inducible chicken lysozyme gene. J Biol Chem 280:27552-60 (2005).
PubMed: 15923188
- Fish JE et al. The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. J Biol Chem 280:24824-38 (2005).
PubMed: 15870070
- Wysocka J et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121:859-72 (2005).
PubMed: 15960974
- Cui R et al. Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription. J Biol Chem 280:39152-60 (2005).
PubMed: 16203738
- van Dijk K et al. Monomethyl histone H3 lysine 4 as an epigenetic mark for silenced euchromatin in Chlamydomonas. Plant Cell 17:2439-53 (2005).
PubMed: 16100335
- Chow CM et al. Variant histone H3.3 marks promoters of transcriptionally active genes during mammalian cell division. EMBO Rep 6:354-60 (2005).
PubMed: 15776021
- Francis J et al. Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription. J Biol Chem 280:36244-53 (2005).
PubMed: 16141209
- Zhang L et al. Altered nucleosome occupancy and histone H3K4 methylation in response to 'transcriptional stress'. EMBO J 24:2379-90 (2005).
PubMed: 15944735
- Loppin B et al. The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus. Nature 437:1386-90 (2005).
ICC/IF;
Fruit fly (Drosophila melanogaster).
PubMed: 16251970
- Perkins EJ et al. Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition. Nucleic Acids Res 32:1942-7 (2004).
PubMed: 15051812
- Alsford S & Horn D Trypanosomatid histones. Mol Microbiol 53:365-72 (2004).
PubMed: 15228519
- Khalil AM et al. Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis. Proc Natl Acad Sci U S A 101:16583-7 (2004).
PubMed: 15536132
- Daniel JA et al. Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription. J Biol Chem 279:1867-71 (2004).
PubMed: 14660634
- Bean CJ et al. Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegans. Nat Genet 36:100-5 (2004).
PubMed: 14702046
- Schneider R et al. Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol 6:73-7 (2004).
PubMed: 14661024
- Kimura AP et al. Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation. Mol Endocrinol 18:1018-32 (2004).
PubMed: 14715931
- Lawrence RJ et al. A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance. Mol Cell 13:599-609 (2004).
PubMed: 14992728
- An W et al. Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53. Cell 117:735-48 (2004).
PubMed: 15186775
- Li T et al. Activating and silencing histone modifications form independent allelic switch regions in the imprinted Gnas gene. Hum Mol Genet 13:741-50 (2004).
PubMed: 14962976
- Lau JC et al. Tissue-specific and imprinted epigenetic modifications of the human NDN gene. Nucleic Acids Res 32:3376-82 (2004).
PubMed: 15247330
- Dichtl B et al. Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA 10:965-77 (2004).
PubMed: 15146080
- Su RC et al. Dynamic assembly of silent chromatin during thymocyte maturation. Nat Genet 36:502-6 (2004).
PubMed: 15098035
- Oh S et al. A mechanism related to the yeast transcriptional regulator Paf1c is required for expression of the Arabidopsis FLC/MAF MADS box gene family. Plant Cell 16:2940-53 (2004).
PubMed: 15472079
- Vaquero A et al. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell 16:93-105 (2004).
PubMed: 15469825
- Sarraf SA & Stancheva I Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell 15:595-605 (2004).
PubMed: 15327775
- Biron VL et al. Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development. Dev Biol 276:337-51 (2004).
PubMed: 15581869
- Sullivan BA & Karpen GH Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struct Mol Biol 11:1076-83 (2004).
PubMed: 15475964
- Ezhkova E & Tansey WP Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3. Mol Cell 13:435-42 (2004).
PubMed: 14967150
- Pontes O et al. Natural variation in nucleolar dominance reveals the relationship between nucleolus organizer chromatin topology and rRNA gene transcription in Arabidopsis. Proc Natl Acad Sci U S A 100:11418-23 (2003).
PubMed: 14504406
- Kim J et al. Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor. Nucleic Acids Res 31:6741-7 (2003).
PubMed: 14627807
- Morillon A et al. Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. Cell 115:425-35 (2003).
PubMed: 14622597
- Santos-Rosa H et al. Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol Cell 12:1325-32 (2003).
PubMed: 14636589
- Sridharan R et al. Role of the murine reprogramming factors in the induction of pluripotency. Cell 136:364-77 (2009).
ChIP/Chip.
PubMed: 19167336
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