Anti-Hepatocyte Specific Antigen 抗体 [OCH1E5] (ab190706)
Key features and details
- Mouse monoclonal [OCH1E5] to Hepatocyte Specific Antigen
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Hepatocyte Specific Antigen antibody [OCH1E5]
Hepatocyte Specific Antigen 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [OCH1E5] to Hepatocyte Specific Antigen -
由来種
Mouse -
特異性
Hepatocyte specific antigens are useful in studying hepatocellular tumors. They may be useful in differentiating clear cell hepatocellular carcinomas from other clear cell malignancies. They have been shown in the literature to be useful in differentiating hepatoblastoma of embryonal type from small round cell tumors of childhood. Hepatcoyte labels an antigen in the mitochondrial fraction of the liver homogenates. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human Hepatocyte Specific Antigen. Extract of a formalin-fixed, rejected-allograft of a Human liver.
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ポジティブ・コントロール
- IHC: Liver or Hepatocellular Carcinoma.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS -
Concentration information loading...
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特記事項(精製)
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G -
ポリ/モノ
モノクローナル -
クローン名
OCH1E5 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab190706の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 1 - 2 µg/ml.
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特記事項 |
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IHC-P
Use a concentration of 1 - 2 µg/ml. |
ターゲット情報
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関連性
Hepatoblastoma is the most common primary tumor of the liver in children. The use of specific hepatocyte markers and also of alpha Fetoprotein or carcinoembryonic antigen are useful for the identification of normal and malignant fetal hepatocytes.
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Hepatocellular Carcinoma tissue labelling Hepatocyte Specific Antigen with ab190706 at 1-2 µg/mL for 30 minutes at room temperature. Tissues were heated in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Liver tissue labelling Hepatocyte Specific Antigen with ab190706 at 1-2 µg/mL for 30 minutes at room temperature. Tissues were heated in 1mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab190706 は 4 報の論文で使用されています。
- Song G et al. Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma. Nat Commun 13:1642 (2022). PubMed: 35347134
- Bertol BC et al. HLA-G liver expression and HLA-G extended haplotypes are associated with chronic hepatitis C in HIV-negative and HIV-coinfected patients. Clin Immunol 217:108482 (2020). PubMed: 32470543
- Zhang J et al. Overexpression of Epcam and CD133 Correlates with Poor Prognosis in Dual-phenotype Hepatocellular Carcinoma. J Cancer 11:3400-3406 (2020). PubMed: 32231746
- Xue R et al. Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes. Cancer Cell 35:932-947.e8 (2019). PubMed: 31130341