Anti-HSPA6 抗体 (ab69408)
Key features and details
- Rabbit polyclonal to HSPA6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-HSPA6 antibody
HSPA6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HSPA6 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide from C-terminus of Human HSPA6, conjugated to KLH
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ポジティブ・コントロール
- Heat shocked HeLa cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab69408の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa). |
ターゲット情報
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機能
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. -
配列類似性
Belongs to the heat shock protein 70 family. - Information by UniProt
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参照データベース
- Entrez Gene: 3310 Human
- Omim: 140555 Human
- SwissProt: P17066 Human
- Unigene: 654614 Human
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別名
- Heat shock 70 kDa protein 6 antibody
- Heat shock 70 kDa protein B' antibody
- Heat shock 70 kDa protein B'' antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab69408 は 4 報の論文で使用されています。
- Xie F et al. CircPTPRA blocks the recognition of RNA N6-methyladenosine through interacting with IGF2BP1 to suppress bladder cancer progression. Mol Cancer 20:68 (2021). PubMed: 33853613
- Fa J et al. Long Noncoding RNA lnc-TSSK2-8 Activates Canonical Wnt/ß-Catenin Signaling Through Small Heat Shock Proteins HSPA6 and CRYAB. Front Cell Dev Biol 9:660576 (2021). PubMed: 34041241
- Zhang X et al. Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment. Oxid Med Cell Longev 2019:1659468 (2019). PubMed: 31281566
- Gogliotti RG et al. Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic Target. J Pharmacol Exp Ther 365:291-300 (2018). PubMed: 29523700