Anti-HIV1 p24 抗体 (ab53841)
Key features and details
- Goat polyclonal to HIV1 p24
- Suitable for: ICC/IF, WB, IHC-Fr
- Reacts with: Human immunodeficiency virus
- Isotype: IgG
製品の概要
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製品名
Anti-HIV1 p24 antibody
HIV1 p24 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to HIV1 p24 -
由来種
Goat -
特異性
ab53841 recognises the HIV1 viral capsid p24 protein encoded by the gag gene along with p6, p7 and p17 which provide structural elements of the virus. -
アプリケーション
適用あり: ICC/IF, WB, IHC-Frmore details -
種交差性
交差種: Human immunodeficiency virus -
免疫原
Native p24, from strain IIIB
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Proprietary Purification -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53841の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use at an assay dependent concentration.
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WB |
1/200 - 1/2000. Predicted molecular weight: 24 kDa.
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IHC-Fr |
Use at an assay dependent concentration.
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特記事項 |
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ICC/IF
Use at an assay dependent concentration. |
WB
1/200 - 1/2000. Predicted molecular weight: 24 kDa. |
IHC-Fr
Use at an assay dependent concentration. |
ターゲット情報
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関連性
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
細胞内局在
Membrane -
参照データベース
- SwissProt: P04585 Human immunodeficiency virus
- SwissProt: P12497 Human immunodeficiency virus
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別名
- CA antibody
- Capsid protein p24 antibody
- HIV-1 Gag p24 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (8)
ab53841 は 8 報の論文で使用されています。
- Shytaj IL et al. Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress. EMBO Mol Med 13:e13901 (2021). PubMed: 34289240
- Lutgen V et al. HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog 16:e1008381 (2020). PubMed: 32525948
- Peyret H et al. Covalent protein display on Hepatitis B core-like particles in plants through the in vivo use of the SpyTag/SpyCatcher system. Sci Rep 10:17095 (2020). PubMed: 33051543
- Gonzales B et al. Type I Phosphatidylinositol-4-Phosphate 5-Kinases a and ? Play a Key Role in Targeting HIV-1 Pr55Gag to the Plasma Membrane. J Virol 94:N/A (2020). PubMed: 32376619
- Quispe Calla NE et al. Exogenous oestrogen inhibits genital transmission of cell-associated HIV-1 in DMPA-treated humanized mice. J Int AIDS Soc 21:N/A (2018). PubMed: 29334191
- Suh HS et al. Evidence of the innate antiviral and neuroprotective properties of progranulin. PLoS One 9:e98184 (2014). WB . PubMed: 24878635
- Liu R et al. HIV Infection in gastric epithelial cells. J Infect Dis 208:1221-30 (2013). PubMed: 23852124
- Hughes AJ & Herr AE Microfluidic Western blotting. Proc Natl Acad Sci U S A : (2012). WB . PubMed: 23223527