Anti-Granulocytes 抗体 [SPM250] (ab75701)
Key features and details
- Mouse monoclonal [SPM250] to Granulocytes
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
製品の概要
-
製品名
Anti-Granulocytes antibody [SPM250]
Granulocytes 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [SPM250] to Granulocytes -
由来種
Mouse -
特異性
ab75701 reacts with early precursor and mature forms of human myeloid cells. We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human Granulocytes. Nuclei from pokeweed mitogen stimulated peripheral blood lymphocytes.
-
ポジティブ・コントロール
- Human tonsil or lymph node tissue
-
特記事項
ab75701 can be useful for the detection of myeloid leukemias and granulocytic sarcomas and also can be used as a marker of granulocytes in normal tissues or inflammatory processes.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: BSA, 0.0268% PBS -
Concentration information loading...
-
精製度
Protein G purified -
一次抗体 備考
ab75701 can be useful for the detection of myeloid leukemias and granulocytic sarcomas and also can be used as a marker of granulocytes in normal tissues or inflammatory processes. -
ポリ/モノ
モノクローナル -
クローン名
SPM250 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab75701の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
1/50.
|
特記事項 |
---|
IHC-P
1/50. |
ターゲット情報
-
関連性
Granulocytes are a type of white blood cell filled with microscopic granules that are little sacs containing enzymes, compounds that digest microorganisms. They are part of the innate immune system and have somewhat nonspecific, broad-based activity. They do not respond exclusively to specific antigens, as do B-cells and T-cells. Neutrophils, eosinophils and basophils are all types of granulocytes. They are named by the staining features of their granules in the laboratory: Neutrophils have "neutral" subtle granules; Eosinophils have prominent granules that stain readily with the acid dye eosin; and Basophils have prominent granules that stain readily basic (non acidic) dyes.
画像
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab75701 は 1 報の論文で使用されています。
- Kawamoto T et al. Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab. J Gastroenterol 50:467-79 (2015). PubMed: 25112701