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Product name
Anti-FGF basic antibody
FGF basic 抗体 (27件) 一覧
Description
Rabbit polyclonal to FGF basic
Tested applications
WB, IHC-P, IHC-Frmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
A synthetic peptide from the internal part of human, mouse, chicken FGF basic conjugated to an immunogenic carrier protein
Properties
Form
Lyophilised:
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Concentration
Concentration information loading...
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Developmental Biology >> Organogenesis >> Excretory system development >> Kidney development
Cancer >> Invasion/microenvironment >> Angiogenesis >> Angiogenic growth factors
Cancer >> Growth factors >> FGF
Stem Cells >> Neural Stem Cells >> Extracellular
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Growth Factors/Hormones >> FGF
Cardiovascular >> Angiogenesis >> Growth Factors >> FGF >> FGF
Applications
Show applications key
Our Abpromise guarantee covers the use of ab72316 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/300 - 1/3000. Predicted molecular weight: 17 kDa.This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
IHC-P: 1/300 - 1/3000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-Fr
IHC-Fr: 1/300 - 1/3000.IHC-Fr: 1/300 - 1/3000.
Target
Function
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
Tissue specificity
Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
Sequence similarities
Belongs to the heparin-binding growth factors family.
Post-translational
modifications
Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.
Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
Cellular localization
Secreted. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane.
Target information above from: UniProt accessionP09038
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Basic fibroblast growth factor antibody
- BFGF antibody
- FGF 2 antibody
see all
Database links
- Entrez Gene: 2247 Human
- Entrez Gene: 14173 Mouse
- Omim: 134920 Human
- SwissProt: P09038 Human
- SwissProt: P15655 Mouse
- Unigene: 284244 Human
- Unigene: 473689 Mouse
References for Anti-FGF basic antibody (ab72316)
ab72316 has not yet been referenced specifically in any publications.
Publishing research using ab72316? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"