Anti-FAM13A 抗体 (ab122440)
Key features and details
- Rabbit polyclonal to FAM13A
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FAM13A antibody -
製品の詳細
Rabbit polyclonal to FAM13A -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human FAM13A aa 904-973 (C terminal).
Sequence:TDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPELLE HLQEMREEKKRIRKKLRDFE
Database link: O94988 -
ポジティブ・コントロール
- IHC-P: Human testis, small intestine, Fallopian tube and cerebral cortex Tissue ICC/IF: Human cell line U-2 OS
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab122440の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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特記事項 |
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IHC-P
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
ターゲット情報
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組織特異性
Isoform 1 is widely expressed, with highest expression in skeletal muscle, thymus, brain and lung. Isoform 3 is less abundant than isoform 1 and predominantly expressed in kidney, pancreas,liver, lung and thymus. -
配列類似性
Belongs to the FAM13 family.
Contains 1 Rho-GAP domain. - Information by UniProt
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参照データベース
- Entrez Gene: 10144 Human
- Omim: 613299 Human
- SwissProt: O94988 Human
- Unigene: 97270 Human
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別名
- FA13A_HUMAN antibody
- Fam13a antibody
- FAM13A1 antibody
see all
画像
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Immunohistochemical analysis of human small intestine labeling FAM13A with ab122440 showing strong cytoplasmic positivity in glandular cells.
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Immunocytochemistry/ Immunofluorescence analysis of U2-OS cells labeling FAM13A with ab122440 showing localization to nucleoli, cytosol & cell junctions.
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Immunohistochemical analysis of human fallopian tube labeling FAM13A with ab122440 showing strong cytoplasmic positivity in glandular cells.
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Immunohistochemical analysis of human cerebral cortex labeling FAM13A with ab122440 showing strong cytoplasmic positivity in neurons.
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Immunohistochemical analysis of human testis labeling FAM13A with ab122440 showing strong cytoplasmic positivity in glandular cells in seminiferous duct.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab122440 は 3 報の論文で使用されています。
- Ziólkowska-Suchanek I et al. Hypoxia-Induced FAM13A Regulates the Proliferation and Metastasis of Non-Small Cell Lung Cancer Cells. Int J Mol Sci 22:N/A (2021). PubMed: 33919074
- Yao MY et al. microRNA-328 in exosomes derived from M2 macrophages exerts a promotive effect on the progression of pulmonary fibrosis via FAM13A in a rat model. Exp Mol Med 51:63 (2019). PubMed: 31164635
- Ziólkowska-Suchanek I et al. FAM13A as a Novel Hypoxia-Induced Gene in Non-Small Cell Lung Cancer. J Cancer 8:3933-3938 (2017). PubMed: 29187867