Anti-EREG 抗体 [MM0265- 12Y4] (ab89291)
Key features and details
- Mouse monoclonal [MM0265- 12Y4] to EREG
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-EREG antibody [MM0265- 12Y4]
EREG 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0265- 12Y4] to EREG -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length Human EREG protein.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
MM0265- 12Y4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89291の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration.
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特記事項 |
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WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. -
組織特異性
In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. -
配列類似性
Contains 1 EGF-like domain. -
細胞内局在
Cell membrane and Secreted > extracellular space. - Information by UniProt
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参照データベース
- Entrez Gene: 2069 Human
- Omim: 602061 Human
- SwissProt: O14944 Human
- Unigene: 115263 Human
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別名
- Epiregulin antibody
- EPR antibody
- ER antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab89291 は 1 報の論文で使用されています。
- Oliveras-Ferraros C et al. Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells. Br J Cancer 106:1406-14 (2012). PubMed: 22491422