Anti-DPP8 抗体 (ab113226)
Key features and details
- Rabbit polyclonal to DPP8
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: n/a
製品の概要
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製品名
Anti-DPP8 antibody
DPP8 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DPP8 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human DPP8 aa 1-39 conjugated to Keyhole Limpet Haemocyanin (KLH).
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ポジティブ・コントロール
- Human placenta and prostate tissues; A431 cell lysate; HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol (glycerin, glycerine), Tris glycine -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
研究分野
関連製品
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Compatible Secondaries
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113226の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 103 kDa.
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IHC-P |
Use a concentration of 10 µg/ml.
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ICC/IF |
1/100 - 1/200.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 103 kDa. |
IHC-P
Use a concentration of 10 µg/ml. |
ICC/IF
1/100 - 1/200. |
ターゲット情報
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機能
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function. -
組織特異性
Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain. -
配列類似性
Belongs to the peptidase S9B family. DPPIV subfamily. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 54878 Human
- Omim: 606819 Human
- SwissProt: Q6V1X1 Human
- Unigene: 591106 Human
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別名
- Dipeptidyl peptidase 8 antibody
- Dipeptidyl peptidase IV-related protein 1 antibody
- Dipeptidyl peptidase VIII antibody
see all
画像
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Anti-DPP8 antibody (ab113226) at 1/1000 dilution + A431 whole cell lysate at 30 µg
Predicted band size: 103 kDa
7.5% SDS PAGE. -
ab113226 at 1/200 dilution staining DPP8 in paraformaldehyde-fixed HeLa cells by Immunofluorescence. The lower image is merged with DNA probe.
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ab113226, at 10µg/ml, staining DPP8 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry.
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ab113226, at 10µg/ml, staining DPP8 in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab113226 は 2 報の論文で使用されています。
- Liu HF et al. Dipeptidyl peptidase-8 induces sorafenib resistance via binding with c-Rel to mediate NF-κB signaling in hepatocellular carcinoma. Cell Biol Int 46:213-221 (2022). PubMed: 34719075
- Chen Y et al. Targeting dipeptidyl peptidase 8 genes inhibits proliferation, migration and invasion by inhibition of cyclin D1 and MMP2MMP9 signal pathway in cervical cancer. J Gene Med 20:e3056 (2018). PubMed: 30225951