Anti-Choline Acetyltransferase 抗体 (ab6168)
Key features and details
- Rabbit polyclonal to Choline Acetyltransferase
- Suitable for: IHC-FrFl
- Reacts with: Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Choline Acetyltransferase antibody
Choline Acetyltransferase 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Choline Acetyltransferase -
由来種
Rabbit -
特異性
Extensive immunohistochemistry indicates localisation to cholinergic nervous system only. Will stain cholinergic neurons in rat central and peripheral nervous systems. -
アプリケーション
適用あり: IHC-FrFlmore details -
種交差性
交差種: Rat
交差が予測される動物種: Chicken, Human, Pig, Non human primates非交差種: Sheep -
免疫原
Synthetic peptide:
H-GLFSSYRLPGHTQDTLVAQKSS
conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 168-189 of Choline Acetyltransferase. -
特記事項
This antibody appears to have identical characteristics to those described by Benecke et al (1993). The antigen is the same. It is an excellent reagent for immunohistochemistry for both peripheral and central nervous system, staining both cell bodies and nerve terminals.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab6168の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-FrFl |
Use at an assay dependent concentration.
|
特記事項 |
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IHC-FrFl
Use at an assay dependent concentration. |
ターゲット情報
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機能
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. -
関連疾患
Myasthenic syndrome, congenital, 6, presynaptic -
配列類似性
Belongs to the carnitine/choline acetyltransferase family. - Information by UniProt
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参照データベース
- Entrez Gene: 1103 Human
- Entrez Gene: 396896 Pig
- Entrez Gene: 290567 Rat
- Omim: 118490 Human
- SwissProt: P28329 Human
- SwissProt: P13222 Pig
- SwissProt: P32738 Rat
- Unigene: 302002 Human
see all -
別名
- Acetyl CoA choline O acetyltransferase antibody
- Acetyl CoA:choline O acetyltransferase antibody
- ChAT antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (13)
ab6168 は 13 報の論文で使用されています。
- Liu Z et al. Activation of Neural Modeling-Related Genes in the Heart of Mice after Gamma Irradiation. Comput Math Methods Med 2021:8522417 (2021). PubMed: 35003326
- Li L et al. Electro-Acupuncture Improve the Early Pattern Separation in Alzheimer's Disease Mice via Basal Forebrain-Hippocampus Cholinergic Neural Circuit. Front Aging Neurosci 13:770948 (2021). PubMed: 35185516
- Zhu Q et al. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Mol Med Rep 21:1172-1180 (2020). PubMed: 31922229
- Xiao Q et al. A new GABAergic somatostatin projection from the BNST onto accumbal parvalbumin neurons controls anxiety. Mol Psychiatry N/A:N/A (2020). PubMed: 32555286
- Kannan A et al. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy. Brain 143:69-93 (2020). PubMed: 31828288