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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdc7 Kinase antibody [SPM171], prediluted (ab53919)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdc7 Kinase antibody [SPM171], prediluted (ab53919)
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Product Name 

Cdc7 Kinase antibody [SPM171], prediluted

 

Cdc7 Kinase 抗体 (8件) 一覧

Product type 

Primary antibodies

Description 

Mouse monoclonal [SPM171] to Cdc7 Kinase, prediluted

Immunogen 

Recombinant full length protein (Human)

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IHC-P


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: Ready to use for 60 min at room temperature. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Hela cells and tonsil tissue.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Cell cycle >> Kinases/Phosphatases >> Cdks
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Other

Relevance 

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.

 

Cdc7 Kinase antibody [SPM171], prediluted (ab53919)の別名

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8317    (Human)

Omim

    

603311    (Human)

SwissProt

    

O00311    (Human)

Unigene

    

28853    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

SPM171

Isotype 

IgG1

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: Sodium Azide
Constituents: PBS, BSA

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Prediluted

Storage instructions 

Store at +4°C.

 

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See below for Cdc7 Kinase antibody [SPM171], prediluted images, references, products related to ab53919 and other tools.

 

Cdc7 Kinase antibody [SPM171], prediluted images:

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdc7 Kinase antibody [SPM171], prediluted (ab53919)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cdc7 Kinase antibody [SPM171], prediluted (ab53919)

ab53919 staining Cdc7 Kinase in human tonsil by immunohistochemistry. Formalin-fixed paraffin embedded section.

 
 

Search PubMed (MEDLINE) for references to Cdc7 Kinase

 

Cdc7 Kinase antibody [SPM171], prediluted - more information

Customer reviews (feedback) regarding Cdc7 Kinase antibody [SPM171], prediluted

Customer FAQs regarding Cdc7 Kinase antibody [SPM171], prediluted

Protocols for Cdc7 Kinase antibody [SPM171], prediluted

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Cdc7 Kinase antibody [SPM171], prediluted - related products:

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Slides

 

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