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- Cdc7 Kinase antibody [SPM171] (ab17880)
![- Cdc7 Kinase antibody [SPM171] (ab17880)](/ps/datasheet/images/ab17880_1.jpg)
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Product Name
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Cdc7 Kinase antibody [SPM171]
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Cdc7 Kinase 抗体 (8件) 一覧
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [SPM171] to Cdc7 Kinase
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Immunogen
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Recombinant full length protein (Human).
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P, IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Detects a band of approximately 55 kDa (predicted molecular weight: 64 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Hela cells. Tonsil.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Cell cycle >> Kinases/Phosphatases >> Cdks
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Other
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Relevance
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DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.
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Cdc7 Kinase antibody [SPM171] (ab17880)の別名 |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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SPM171
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: Sodium Azide
Constituents: BSA, 10mM PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.200 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Abcam では全ての製品情報を一元管理しており、 Cdc7 Kinase antibody [SPM171] について私たちが知りうる全ての情報がこのデータシートでご覧いただけます。ご不明な点がありましたら、 お問い合わせください。 |
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See below for Cdc7 Kinase antibody [SPM171] images, references, products related to ab17880 and other tools.
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Cdc7 Kinase antibody [SPM171] images:
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 - Cdc7 Kinase antibody [SPM171] (ab17880)
Immunohistochemistry on human tonsil using ab17880.
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Search PubMed (MEDLINE) for references to Cdc7 Kinase
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Cdc7 Kinase antibody [SPM171] - more information
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Customer reviews (feedback) regarding Cdc7 Kinase antibody [SPM171] |
Customer FAQs regarding Cdc7 Kinase antibody [SPM171] |
Protocols for Cdc7 Kinase antibody [SPM171] |
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Cdc7 Kinase antibody [SPM171] - related products:
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Cdc7 Kinase antibody [SPM171] - other tools:
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Contact Abcam with a Technical Enquiry about Cdc7 Kinase antibody [SPM171] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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