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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Synthesis >> Other
Overview
Product name
Anti-Cdc6 antibody [Cdc6 9H8/5]
Cdc6 抗体 (11件) 一覧
Description
Mouse monoclonal [Cdc6 9H8/5] to Cdc6
Tested applications
IP, WBmore details
Cross reactivity
Reacts with
Saccharomyces cerevisiae
Immunogen
C terminal protein (Saccharomyces cerevisiae)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
Cdc6 9H8/5
Myeloma
unknown
Isotype
IgG1
Light chain type
unknown
Research areas
Cell Biology >> Cell Cycle >> Cell Division >> Other cell division antibodies
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Synthesis >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab20150 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 58 kDa.
Target
Function
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Sequence similarities
Belongs to the CDC6/cdc18 family.
Cellular localization
Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells.
Target information above from: UniProt accessionQ99741
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Cdc 18L antibody
- Cdc 6 antibody
- CDC18 (cell division cycle 18, S.pombe, homolog) like antibody
see all
Database links
- SwissProt: P09119 Saccharomyces cerevisiae
References for Anti-Cdc6 antibody [Cdc6 9H8/5] (ab20150)
This product has been referenced in:
- Zhang JYet al. Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia. Cancer Res 67:3827-34 (2007). WB.Read more (PubMed: 17440097) »
- Perkins Get al. Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis. EMBO J 20:4836-45 (2001).Read more (PubMed: 11532947) »
See all 3 publications for this product
Publishing research using ab20150? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"