Anti-Carboxymethyl Lysine 抗体 [CMS-10] (ab30922)
Key features and details
- Mouse monoclonal [CMS-10] to Carboxymethyl Lysine
- Suitable for: ELISA, IHC-Fr, IHC-P
- Reacts with: Species independent
- Isotype: IgG1
製品の概要
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製品名
Anti-Carboxymethyl Lysine antibody [CMS-10]
Carboxymethyl Lysine 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CMS-10] to Carboxymethyl Lysine -
由来種
Mouse -
アプリケーション
適用あり: ELISA, IHC-Fr, IHC-Pmore details -
種交差性
交差種: Species independent -
免疫原
N epsilon (Carboxymethyl) Lysine (CML) conjugated to KLH.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.1% Proclin 150
Ascites in stabilized buffer, containing 50% Block Ace (Casein-containing solution) and 0.1% ProClin as a preservative. -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
CMS-10 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab30922の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use a concentration of 0.1 - 0.5 µg/ml.
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IHC-Fr |
Use a concentration of 2 µg/ml.
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IHC-P | (1) |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use a concentration of 0.1 - 0.5 µg/ml. |
IHC-Fr
Use a concentration of 2 µg/ml. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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関連性
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy. -
別名
- CML antibody
- N Epsilon (Carboxymethyl) Lysine antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab30922 は 2 報の論文で使用されています。
- Portal-Núñez S et al. Adverse Effects of Diabetes Mellitus on the Skeleton of Aging Mice. J Gerontol A Biol Sci Med Sci 71:290-9 (2016). PubMed: 26386012
- de la Maza MP et al. Weight increase is associated with skeletal muscle immunostaining for advanced glycation end products, receptor for advanced glycation end products, and oxidation injury. Rejuvenation Res 11:1041-8 (2008). IHC-P . PubMed: 19086911