Anti-Homeobox protein cut-like 1 抗体 (ab73885)
Key features and details
- Rabbit polyclonal to Homeobox protein cut-like 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Homeobox protein cut-like 1 antibody
Homeobox protein cut-like 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Homeobox protein cut-like 1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide corresponding to Human Homeobox protein cut-like 1 (N terminal).
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ポジティブ・コントロール
- WB: Extracts from K562 cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab73885の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 164 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 164 kDa. |
ターゲット情報
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関連性
Function: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). Similarity: Belongs to the CUT homeobox family. -
細胞内局在
Nucleus -
参照データベース
- Entrez Gene: 1523 Human
- Omim: 116896 Human
- SwissProt: P39880 Human
- SwissProt: P70403 Mouse
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別名
- CCAAT displacement protein antibody
- CDP antibody
- CDP/Cut antibody
see all
画像
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All lanes : Anti-Homeobox protein cut-like 1 antibody (ab73885) at 1/500 dilution
Lane 1 : extracts from K562 cells
Lane 2 : extracts from K562 cells with immunizing peptide at 10 µg
Lysates/proteins at 20 µg per lane.
Predicted band size: 164 kDa
Observed band size: 164 kDa
Additional bands at: 75 kDa, 80 kDa. We are unsure as to the identity of these extra bands.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab73885 は 1 報の論文で使用されています。
- Wong CC et al. Inactivating CUX1 mutations promote tumorigenesis. Nat Genet 46:33-8 (2014). WB . PubMed: 24316979