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Western blot - CRMP4 antibody (ab54819)
Western blot - CRMP4 antibody (ab54819)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-CRMP4 antibody(ab54819)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-CRMP4 antibody(ab54819)
(enlarge)


Product Name 

CRMP4 antibody

 

CRMP4 抗体 (3件) 一覧

Product type 

Primary antibodies

Description 

Mouse monoclonal to CRMP4

Immunogen 

Recombinant fragment: GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD EGVRSASKR, corresponding to amino acids 457-556 of Human CRMP4
BLAST 'GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD ' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IHC-P, WB


Abreviews 

Customer reviews
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Application notes 
(see key)

Recommended dilutions
IHC-P: Use at a concentration of 3 µg/ml.
WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 62 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic. Cell projection, growth cone (By similarity). Note: Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.

Research areas 

Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other

Relevance 

The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.

 

CRMP4 antibody (ab54819)の別名

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

1809    (Human)

Omim

    

601168    (Human)

SwissProt

    

Q14195    (Human)

Unigene

    

519659    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2a

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

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CRMP4 antibody images:

Product image  Western blot - CRMP4 antibody (ab54819)

Western blot - CRMP4 antibody (ab54819)



Predicted band size : 62 kDa


CRMP4 antibody (ab54819) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

 

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-CRMP4 antibody(ab54819)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-CRMP4 antibody(ab54819)

ab54819 at 3 ug/ml staining CRMP4 in human Ovary tissue sections by Immunohistochemistry (Formallin /PFA-fixed paraffin embedded tissue sections)

 
 

Search PubMed (MEDLINE) for references to CRMP4

 

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