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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Overview
Product name
Anti-CRMP4 antibody
CRMP4 抗体 (4件) 一覧
Description
Mouse monoclonal to CRMP4
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD EGVRSASKR, corresponding to amino acids 457-556 of Human CRMP4
GNLHVTQGAG RFIPCSPFSD YVYKRIKARR KMADLHAVPR GMYDGPVFDL TTTPKGGTPA GSARGSPTRP NPPVRNLHQS GFSLSGTQVD EGVRSASKR
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54819 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 62 kDa.
IHC-P: Use a concentration of 3 µg/ml
Target
Relevance
The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.
Cellular localization
Cytoplasmic. Cell projection, growth cone (By similarity). Note: Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Alternative names
- Unc 33 like phosphoprotein antibody
- Collapsin response mediator protein 4 antibody
- Collapsin response mediator protein 4 long antibody
see all
Database links
- Entrez Gene: 1809 Human
- Omim: 601168 Human
- SwissProt: Q14195 Human
- Unigene: 519659 Human
Anti-CRMP4 antibody images:
Western blot - CRMP4 antibody (ab54819)
CRMP4 antibody (ab54819) at 1ug/lane + Jurkat cell lysate at 25ug/lane.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-CRMP4 antibody(ab54819)
ab54819 at 3 ug/ml staining CRMP4 in human Ovary tissue sections by Immunohistochemistry (Formallin /PFA-fixed paraffin embedded tissue sections)
References for Anti-CRMP4 antibody (ab54819)
ab54819 has not yet been referenced specifically in any publications.
Publishing research using ab54819? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"