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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Overview
Product name
Anti-CRMP4 antibody
CRMP4 抗体 (4件) 一覧
Description
Rabbit polyclonal to CRMP4
Specificity
No cross reactivity was detected with CRMP1, CRMP2, CRMP3 or CRMP5.
Tested applications
WB, IHC-Fr, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator (Type 4).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
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Western blot - CRMP4 antibody (ab36204)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab36204 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/2000Predicted molecular weight: 65 kDa.
IHC-Fr
IHC-Fr: 1/500IHC-Fr: 1/500
IHC-P
IHC-P: 1/500IHC-P: 1/500
Target
Relevance
The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.
Cellular localization
Cytoplasmic. Cell projection, growth cone (By similarity). Note: Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
Alternative names
- Unc 33 like phosphoprotein antibody
- Collapsin response mediator protein 4 antibody
- Collapsin response mediator protein 4 long antibody
see all
Database links
- Entrez Gene: 1809 Human
- Entrez Gene: 22240 Mouse
- Entrez Gene: 25418 Rat
- Omim: 601168 Human
- SwissProt: Q14195 Human
- SwissProt: Q62188 Mouse
- SwissProt: Q62952 Rat
- Unigene: 519659 Human
see all
Anti-CRMP4 antibody images:
Western blot - CRMP4 antibody (ab36204)
All lanes : Anti-CRMP4 antibody (ab36204)
Lane 1 : E.coli lysate transformed with cDNA of human CRMP1
Lane 2 : E.coli lysate transformed with cDNA of human CRMP2
Lane 3 : E.coli lysate transformed with cDNA of human CRMP3
Lane 4 : E.coli lysate transformed with cDNA of human CRMP4
Lane 5 : E.coli lysate transformed with cDNA of human CRMP5
Predicted band size : 65 kDa
Observed band size : 65 kDa
References for Anti-CRMP4 antibody (ab36204)
ab36204 has not yet been referenced specifically in any publications.
Publishing research using ab36204? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"