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Western blot - CRMP4 antibody (ab36204)
Western blot - CRMP4 antibody (ab36204)
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Product Name 

CRMP4 antibody

 

CRMP4 抗体 (3件) 一覧

Product type 

Primary antibodies

Description 

Rabbit polyclonal to CRMP4

Immunogen 

A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator (Type 4).

Reacts with 
(species key)

Hu, Ms, Rat

Specificity 

No cross reactivity was detected with CRMP1, CRMP2, CRMP3 or CRMP5.

Tested applications 
(see key)

IHC-Fr, IHC-P, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-Fr: 1/500.
IHC-P: 1/500.
WB: 1/2000. Predicted molecular weight: 65 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic. Cell projection, growth cone (By similarity). Note: Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.

Research areas 

Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other

Relevance 

The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.

 

CRMP4 antibody (ab36204)の別名

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

1809    (Human)
22240    (Mouse)
25418    (Rat)

Omim

    

601168    (Human)

SwissProt

    

Q14195    (Human)
Q62188    (Mouse)
Q62952    (Rat)

Unigene

    

519659    (Human)
8180    (Mouse)
93365    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: Whole serum

Form 

Liquid

Concentration 

Concentration not determined - その理由

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

 

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See below for CRMP4 antibody images, references, products related to ab36204 and other tools.

 

CRMP4 antibody images:

Product image  Western blot - CRMP4 antibody (ab36204)

Western blot - CRMP4 antibody (ab36204)

All lanes : CRMP4 antibody (ab36204)

Lane 1 : E.coli lysate transformed with cDNA of human CRMP1
Lane 2 : E.coli lysate transformed with cDNA of human CRMP2
Lane 3 : E.coli lysate transformed with cDNA of human CRMP3
Lane 4 : E.coli lysate transformed with cDNA of human CRMP4
Lane 5 : E.coli lysate transformed with cDNA of human CRMP5


Predicted band size : 65 kDa
Observed band size : 65 kDa

 
 

Search PubMed (MEDLINE) for references to CRMP4

 

CRMP4 antibody - more information

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CRMP4 antibody - related products:

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