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Read our guarantee »Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Anti-CRMP4 antibody
CRMP4 抗体 (4件) 一覧
Rabbit polyclonal to CRMP4
CRMP4 protein (Ulip1/TUC4). This antibody has been reported to label early postmitotic neurons in prenatal rat brain. The antibody is not reactive with the proteins TUC-1 (Ulip3/CRMP1), TUC2 (Ulip2/CRMP2) or TUC3 (Ulip4/CRMP3). It does not label neural progenitor or radial glia.
ICC, WB, IP, IHC-FoFrmore details
Reacts with
Mouse, Rat, Cat, Human, Monkey
Synthetic peptide: YDGPVFDLTT TPK, corresponding to C terminal amino acids 499-511 of Human CRMP4
YDGPVFDLTT TPK
Mainly in heart and skeletal muscle. Also expressed strongly in fetal brain and spinal cord.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.2% Sodium Azide
Constituents: Whole serum
Whole antiserum
Polyclonal
IgG
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Our Abpromise guarantee covers the use of ab23951 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ICC: 1/5000 - 1/10000 (DAB detection).
IHC-Fo: 1/5000 - 1/10000 using PFA (DAB detection).
IP: Use at an assay dependent dilution.
WB: 1/10000 - 1/100000 using alkaline phosphatase. Predicted molecular weight: 62 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.
Cytoplasmic. Cell projection, growth cone (By similarity). Note: Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
This product has been referenced in:
See all 2 publications for this product
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