Anti-CDC42 binding protein kinase alpha 抗体 (ab95886)
Key features and details
- Rabbit polyclonal to CDC42 binding protein kinase alpha
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CDC42 binding protein kinase alpha antibody
CDC42 binding protein kinase alpha 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CDC42 binding protein kinase alpha -
由来種
Rabbit -
アプリケーション
適用あり: IPmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla, Orangutan, Elephant -
免疫原
Synthetic peptide, corresponding to a region between residues 1610 and 1660 of Human CDC42 binding protein kinase alpha (CAH71185.1).
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ポジティブ・コントロール
- HeLa whole cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab95886 was affinity purified using an epitope specific to CDC42 binding protein kinase alpha immobilized on solid support. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95886の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IP |
Use at 2-5 µg/mg of lysate.
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特記事項 |
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IP
Use at 2-5 µg/mg of lysate. |
ターゲット情報
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機能
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation. -
組織特異性
Abundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver. -
配列類似性
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 CNH domain.
Contains 1 CRIB domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain. -
細胞内局在
Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent. - Information by UniProt
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参照データベース
- Entrez Gene: 100054548 Horse
- Entrez Gene: 8476 Human
- Entrez Gene: 226751 Mouse
- Entrez Gene: 114116 Rat
- GenBank: NP_055641 Human
- Omim: 603412 Human
- SwissProt: Q5VT25 Human
- SwissProt: Q3UU96 Mouse
see all -
別名
- A930014J19Rik antibody
- CDC42 binding protein kinase alpha (DMPK like) antibody
- CDC42 binding protein kinase alpha antibody
see all
画像
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Detection of CDC42 binding protein kinase alpha by Western Blot of Immunprecipitate.
An other antibody at 1µg/ml staining CDC42 binding protein kinase alpha in HeLa whole cell lysate immunoprecipitated using ab95886 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection: Chemiluminescence with exposure time of 10 seconds.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab95886 は論文での使用が確認できていません。