Biotin Anti-CD63 抗体 [MEM-259] (ab134331)
Key features and details
- Biotin Mouse monoclonal [MEM-259] to CD63
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
Related conjugates and formulations
製品の概要
-
製品名
Biotin Anti-CD63 antibody [MEM-259]
CD63 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [MEM-259] to CD63 -
由来種
Mouse -
標識
Biotin -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD63. HPB-ALL T cell line
-
ポジティブ・コントロール
- Activated platelets, neutrophils and basophils. Human spleen tissue.
-
特記事項
The antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
-
精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
MEM-259 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab134331の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
|
特記事項 |
---|
Flow Cyt
Use at an assay dependent concentration. |
ターゲット情報
-
機能
This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. -
組織特異性
Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages. -
配列類似性
Belongs to the tetraspanin (TM4SF) family. -
細胞内局在
Cell membrane. Lysosome membrane. Late endosome membrane. Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. - Information by UniProt
-
参照データベース
- Entrez Gene: 967 Human
- Omim: 155740 Human
- SwissProt: P08962 Human
- Unigene: 445570 Human
-
別名
- Lysosomal associated membrane protein 3 antibody
- CD 63 antibody
- CD63 antibody
see all
画像
-
Flow cytometry multicolor surface staining of IgE stimulated peripheral blood mononuclear cells stained usingab134331 (concentration in sample 0.6 μg/mL, Streptavidin APC).
-
Flow cytometry multicolor surface staining of IgE stimulated peripheral blood mononuclear cells stained usingab134331 (concentration in sample 0.6 μg/mL, Streptavidin APC) and anti-human CD203c PE antibody (20 μL reagent / 100 μL of peripheral whole blood).
-
Flow Cytometry analysis of (surface staining) of IgE stimulated human peripheral whole blood using ab134331 (concentration in sample 0.6 μg/mL, Streptavidin APC). CD63 positive CD203c positive basophil granulocytes (red-filled) from neutrophil granulocytes (black-dashed).
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (6)
ab134331 は 6 報の論文で使用されています。
- Temperini ME et al. Antenna-enhanced mid-infrared detection of extracellular vesicles derived from human cancer cell cultures. J Nanobiotechnology 20:530 (2022). PubMed: 36514065
- Wang JM et al. Comparative evaluation of methods for isolating small extracellular vesicles derived from pancreatic cancer cells. Cell Biosci 11:37 (2021). PubMed: 33568197
- Neo SY et al. CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment. J Clin Invest 130:1185-1198 (2020). PubMed: 31770109
- Zhang W et al. Enabling Sensitive Phenotypic Profiling of Cancer-Derived Small Extracellular Vesicles Using Surface-Enhanced Raman Spectroscopy Nanotags. ACS Sens 5:764-771 (2020). PubMed: 32134252
- Fan Z et al. Exosome-specific tumor diagnosis via biomedical analysis of exosome-containing microRNA biomarkers. Analyst 144:5856-5865 (2019). PubMed: 31482867
- Huang L et al. A dual-signal amplification platform for sensitive fluorescence biosensing of leukemia-derived exosomes. Nanoscale 10:20289-20295 (2018). PubMed: 30371719