FITC Anti-CD2 抗体 [LT2] (ab27995)
Key features and details
- FITC Mouse monoclonal [LT2] to CD2
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-CD2 antibody [LT2]
CD2 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [LT2] to CD2 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab27995 recognises CD2 expressed by T cells, NK cells and thymocytes. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD2. Normal human peripheral blood lymphocytes.
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特記事項
ab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Protein A purified -
一次抗体 備考
ab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation. -
ポリ/モノ
モノクローナル -
クローン名
LT2 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27995の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 10µl for 106 cells.
Use 10µl for 106 cells, or 100µl of whole blood.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 10µl for 106 cells. Use 10µl for 106 cells, or 100µl of whole blood.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|
ターゲット情報
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機能
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. -
配列類似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 914 Human
- Omim: 186990 Human
- SwissProt: P06729 Human
- Unigene: 523500 Human
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別名
- CD 2 antibody
- CD2 antibody
- CD2 antigen (p50), sheep red blood cell receptor antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (2)
ab27995 は 2 報の論文で使用されています。
- Lin CW et al. CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood 106:3567-74 (2005). PubMed: 16046525
- Beyers AD et al. Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen. Immunol Rev 111:59-77 (1989). PubMed: 2576418