PE/DyLight™ 594 Anti-CD19 抗体 [4G7] (ab178449)
Key features and details
- PE/DyLight™ 594 Mouse monoclonal [4G7] to CD19
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE/DyLight™ 594
- Isotype: IgG1
製品の概要
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製品名
PE/DyLight™ 594 Anti-CD19 antibody [4G7]
CD19 一次抗体 製品一覧 -
製品の詳細
PE/DyLight™ 594 Mouse monoclonal [4G7] to CD19 -
由来種
Mouse -
標識
PE/DyLight™ 594 -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD19. Human CCL (chronic lymphocytic leukemia) cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS, 0.2% BSA
BSA is high-grade and protease free. -
Concentration information loading...
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精製度
Size exclusion -
特記事項(精製)
The purified antibody is conjugated with tandem dye PE-DyLight™594 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
ポリ/モノ
モノクローナル -
クローン名
4G7 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab178449の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 4µl for 106 cells.
or per 100 µl of whole blood |
特記事項 |
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Flow Cyt
Use 4µl for 106 cells. or per 100 µl of whole blood |
ターゲット情報
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機能
Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. -
関連疾患
Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
配列類似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
翻訳後修飾
Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 930 Human
- Omim: 107265 Human
- SwissProt: P15391 Human
- Unigene: 652262 Human
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別名
- Antibody deficiency due to defect in CD19 antibody
- Antibody deficiency due to defect in CD19, included antibody
- AW495831 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab178449 は論文での使用が確認できていません。