FITC Anti-CD177 抗体 [MEM-166] (ab26013)
Key features and details
- FITC Mouse monoclonal [MEM-166] to CD177
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
製品の概要
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製品名
FITC Anti-CD177 antibody [MEM-166]
CD177 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [MEM-166] to CD177 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human
交差が予測される動物種: Non human primates -
免疫原
Tissue, cells or virus corresponding to Human CD177. Human granulocytes
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特記事項
The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading...
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精製度
Size exclusion -
特記事項(精製)
Purity >95% by SDS-PAGE. -
ポリ/モノ
モノクローナル -
クローン名
MEM-166 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab26013の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 20µl for 106 cells.
or 100 µl of whole blood. (The antibody should be used undiluted with the samples). ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 20µl for 106 cells. or 100 µl of whole blood. (The antibody should be used undiluted with the samples). ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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組織特異性
Highly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET). -
配列類似性
Contains 2 UPAR/Ly6 domains. -
翻訳後修飾
N-glycosylated.
A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 57126 Human
- Omim: 162860 Human
- SwissProt: Q8N6Q3 Human
- Unigene: 232165 Human
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別名
- CD177 antibody
- CD177 antigen antibody
- CD177 molecule antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab26013 は 3 報の論文で使用されています。
- Liu H et al. Proteinase 3 expression on the neutrophils of patients with paroxysmal nocturnal hemoglobinuria. Exp Ther Med 15:2525-2532 (2018). PubMed: 29467851
- Herrmann IK et al. Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation. Nanoscale 7:13511-20 (2015). PubMed: 26201870
- Hu N et al. Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration. Arthritis Res Ther 13:R201 (2011). Flow Cyt ; Human . PubMed: 22152684