Anti-CAPRIN2 抗体 (ab122583)
Key features and details
- Rabbit polyclonal to CAPRIN2
- Suitable for: ICC, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CAPRIN2 antibody -
製品の詳細
Rabbit polyclonal to CAPRIN2 -
由来種
Rabbit -
アプリケーション
適用あり: ICC, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
antigen sequence: TPKPRENNVE SQKHSLTSQS QISPKSWGVA TASLIPNDQL LPRKLNTEPK DVPKPVHQPV GSSSTLPKDP VLRKEKLQDL MTQIQGT, corresponding to internal sequence amino acids 544-630 of Human CAPRIN2.
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ポジティブ・コントロール
- IHC-P: Human hippocampus tissue. ICC: Human cell line U-251 MG.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab122583の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC |
Use a concentration of 0.25 - 2 µg/ml.
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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ICC
Use a concentration of 0.25 - 2 µg/ml. |
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. -
組織特異性
Detected in all tissues tested with highest levels of expression in brain and spleen. -
配列類似性
Belongs to the caprin family.
Contains 1 C1q domain. -
発生段階
Expression is highly regulated during erythroid development with increased expression at the stage of differentiation associated with the onset of global nuclear condensation and reduced cell proliferation. -
細胞内局在
Cytoplasm; Mitochondrion. Colocalizes with aggregated mitochondria and Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 65981 Human
- Omim: 610375 Human
- SwissProt: Q6IMN6 Human
- Unigene: 234355 Human
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別名
- C1q domain-containing protein 1 antibody
- C1QDC1 antibody
- CAPR2_HUMAN antibody
see all
画像
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Immunocytochemistry/immunofluorescence analysis of human cell line U-251 MG labelling CAPRIN2 with ab122583 at 2 µg/mL.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human hippocampus tissue labelling CAPRIN2 with ab122583 at 1/50 dilution. Heat mediated antigen retrieval performed with citrate buffer pH 6 before commencing with IHC staining protocol.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab122583 は論文での使用が確認できていません。