Anti-BMX 抗体 [Y396] (ab32153)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [Y396] to BMX
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-BMX antibody [Y396]
BMX 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [Y396] to BMX -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt or ICC/IF -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide within Human BMX aa 50-150. The exact sequence is proprietary.
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ポジティブ・コントロール
- HeLa whole cell lysate (ab150035).
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特記事項
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
Y396 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab32153の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/2000. Detects a band of approximately 75 kDa (predicted molecular weight: 78 kDa).
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特記事項 |
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WB
1/1000 - 1/2000. Detects a band of approximately 75 kDa (predicted molecular weight: 78 kDa). |
ターゲット情報
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機能
Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells. -
組織特異性
Preferentially expressed in epithelial and endothelial cells. -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
Contains 1 Btk-type zinc finger.
Contains 1 PH domain.
Contains 1 protein kinase domain.
Contains 1 SH2 domain. -
ドメイン
SH2 domain mediates interaction with RUFY1. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 660 Human
- Entrez Gene: 12169 Mouse
- Entrez Gene: 367786 Rat
- Omim: 300101 Human
- SwissProt: P51813 Human
- SwissProt: P97504 Mouse
- Unigene: 495731 Human
- Unigene: 504 Mouse
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別名
- Bmx antibody
- BMX non receptor tyrosine kinase antibody
- BMX_HUMAN antibody
see all
画像
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Anti-BMX antibody [Y396] (ab32153) at 1/500 dilution + HeLa cell lysate
Predicted band size: 78 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab32153 は 3 報の論文で使用されています。
- Peng J et al. EPHA3 regulates the multidrug resistance of small cell lung cancer via the PI3K/BMX/STAT3 signaling pathway. Tumour Biol 37:11959-11971 (2016). PubMed: 27101199
- Xiong Y et al. Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases. J Innate Immun 8:171-84 (2016). PubMed: 26457672
- Fiallos E et al. Human cytomegalovirus gene expression in long-term infected glioma stem cells. PLoS One 9:e116178 (2014). PubMed: 25549333