Anti-BMP2 抗体 (ab14933)
Key features and details
- Rabbit polyclonal to BMP2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-BMP2 antibody
BMP2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to BMP2 -
由来種
Rabbit -
特異性
ab14933 detects only the pro-form of the BMP2 -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
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ポジティブ・コントロール
- WB: HeLa, THP, HepG2 and Huh7 cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 30% Glycerol, 0.75% BSA
The antibody is provided in antibody stabilization buffer containing phosphate buffer, pH 7.4, glycerol, stabilizing proteins and preservatives. The exact buffer contents are considered proprietary. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14933の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (6) |
1/500 - 1/1000. Detects a band of approximately 45 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 45 kDa. |
ターゲット情報
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機能
Induces cartilage and bone formation. -
組織特異性
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. -
配列類似性
Belongs to the TGF-beta family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 650 Human
- Omim: 112261 Human
- SwissProt: P12643 Human
- Unigene: 73853 Human
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別名
- BDA2 antibody
- BMP-2 antibody
- BMP-2A antibody
see all
画像
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All lanes : Anti-BMP2 antibody (ab14933) at 1/500 dilution
Lane 1 : HeLa cells
Lane 2 : THP cells
Lane 3 : HepG2 cells
Lane 4 : Huh7 cellsCell extracts were made in protein extraction buffer (Solobuffer) with protease inhibitor cocktail.
Total 40-50ug of protein was applied in each lane on a 10% SDSPAGE,
The gel was transferred on to Immobilon F and blotted with ab14933.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (161)
ab14933 は 161 報の論文で使用されています。
- Wang Y et al. SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling. Cardiovasc Res 118:913-928 (2022). PubMed: 33757126
- Fu X et al. Molecular mechanism of albumin in suppressing invasion and metastasis of hepatocellular carcinoma. Liver Int 42:696-709 (2022). PubMed: 34854209
- Li C et al. The osteoprotective role of USP26 in coordinating bone formation and resorption. Cell Death Differ 29:1123-1136 (2022). PubMed: 35091692
- Skauli N et al. Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes. Front Cell Neurosci 16:878154 (2022). PubMed: 35518645
- Lektemur Alpan A et al. Evaluation of the Effects of Favipiravir Combined with Vitamin C on Alveolar Bone in Rats. J Evol Biochem Physiol 58:430-440 (2022). PubMed: 35599639