Anti-MIST-1 抗体 [6E8/A12/C11P1] - C-terminal (ab110919)
Key features and details
- Mouse monoclonal [6E8/A12/C11P1] to MIST-1 - C-terminal
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-MIST-1 antibody [6E8/A12/C11P1] - C-terminal
MIST-1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [6E8/A12/C11P1] to MIST-1 - C-terminal -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide corresponding to Mouse MIST-1 aa 175-197 (C terminal).
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ポジティブ・コントロール
- Mouse pancreas tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
6E8/A12/C11P1 -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110919の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/50.
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特記事項 |
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IHC-P
1/50. |
ターゲット情報
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機能
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. -
組織特異性
Expressed in brain, liver, spleen and skeletal muscle. -
配列類似性
Contains 1 basic helix-loop-helix (bHLH) domain. -
ドメイン
Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 17341 Mouse
- SwissProt: Q9QYC3 Mouse
- Unigene: 386767 Mouse
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別名
- Basic helix loop helix domain containing class B 8 antibody
- Basic helix loop helix family member a15 antibody
- BHA15_HUMAN antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab110919 は 1 報の論文で使用されています。
- Kim D et al. 3D Organoid Culture From Adult Salivary Gland Tissues as an ex vivo Modeling of Salivary Gland Morphogenesis. Front Cell Dev Biol 9:698292 (2021). PubMed: 34458260