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Products:Signal Transduction >> Signaling Pathway >> Lipid Signaling >> PLC
Overview
Product name
Anti-Angiotensin II Type 2 Receptor antibody
Angiotensin II Type 2 Receptor 抗体 (4件) 一覧
Description
Rabbit polyclonal to Angiotensin II Type 2 Receptor
Tested applications
ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide located on the seven transmembrane domain (7tm_1) of human angiotensin II receptor, type 2 (AGTR2).
Positive control
Synthetic AGTR2 peptide antigen.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
ab31210 is a purified IgG.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cardiovascular >> Blood >> Blood Pressure regulation
Cardiovascular >> Atherosclerosis >> Apoptosis
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> PLC
Applications
Show applications key
Our Abpromise guarantee covers the use of ab31210 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/10000ELISA: 1/10000
Target
Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Tissue specificity
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionP50052
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AGTR 2 antibody
- AGTR2 antibody
- AGTR2_HUMAN antibody
see all
Database links
- Entrez Gene: 186 Human
- Omim: 300034 Human
- SwissProt: P50052 Human
- Unigene: 405348 Human
References for Anti-Angiotensin II Type 2 Receptor antibody (ab31210)
ab31210 has not yet been referenced specifically in any publications.
Publishing research using ab31210? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"