![Western blot - Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445) image](#Angiotensin-II-Type-2-Receptor-Primary-antibodies-ab92445-1.jpg)
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Products:Signal Transduction >> Signaling Pathway >> Lipid Signaling >> PLC
Overview
Product name
Anti-Angiotensin II Type 2 Receptor antibody [EPR3876]
Angiotensin II Type 2 Receptor 抗体 (4件) 一覧
Description
Rabbit monoclonal [EPR3876] to Angiotensin II Type 2 Receptor
Tested applications
WB, IPmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues at the C terminal of Human Angiotensin II Type 2 Receptor.
Positive control
HepG2, 293T, HeLa and fetal liver lysates
General notes
Produced under U.S. Patent No. 5,675,063.
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Storage buffer
Preservative: 0.01% Sodium Azide
Constituents: 40% Glycerol, 0.05% BSA, Tissue culture supernatant, 0.15M Sodium chloride, 50mM Tris glycine, pH 7.4
Purity
Tissue culture supernatant
Clonality
Monoclonal
Clone number
EPR3876
Isotype
IgG
Research areas
Cardiovascular >> Blood >> Blood Pressure regulation
Cardiovascular >> Atherosclerosis >> Apoptosis
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> PLC
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Western blot - Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445)
![Western blot - Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445) image](/ps/datasheet/images/92/ab92445/Angiotensin-II-Type-2-Receptor-Primary-antibodies-ab92445-1.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab92445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
IP
Application notes
IP: 1/10 - 1/100.
WB: 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
Is unsuitable for Flow Cyt, ICC or IHC-P.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Tissue specificity
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionP50052
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AGTR 2 antibody
- AGTR2 antibody
- AGTR2_HUMAN antibody
see all
Database links
- Entrez Gene: 186 Human
- Entrez Gene: 11609 Mouse
- Entrez Gene: 24182 Rat
- Omim: 300034 Human
- SwissProt: P50052 Human
- SwissProt: P35374 Mouse
- SwissProt: Q3US12 Mouse
- SwissProt: P35351 Rat
see all
Anti-Angiotensin II Type 2 Receptor antibody [EPR3876] images:
Western blot - Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445)
All lanes : Anti-Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445) at 1/1000 dilution
Lane 1 : HepG2 cell lysate
Lane 2 : 293T cell lysate
Lane 3 : HeLa cell lysate
Lane 4 : Fetal liver lysate
Lysates/proteins at 10 µg per lane.
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size : 41 kDa
References for Anti-Angiotensin II Type 2 Receptor antibody [EPR3876] (ab92445)
ab92445 has not yet been referenced specifically in any publications.
Publishing research using ab92445? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"