Anti-Amylin/DAP 抗体 (ab55411)
Key features and details
- Rabbit polyclonal to Amylin/DAP
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Amylin/DAP antibody
Amylin/DAP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Amylin/DAP -
由来種
Rabbit -
特異性
ab55411 is expected to detect only the pro-form of Amylin/DAP, not the mature form after removal of the pro-peptide, amino acids 23-31.
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アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human Amylin/DAP.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab55411の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 10 kDa.
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 10 kDa. |
ターゲット情報
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機能
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. -
配列類似性
Belongs to the calcitonin family. -
ドメイン
The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation. -
翻訳後修飾
Amyloid fibrils are degraded by IDE. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3375 Human
- Omim: 147940 Human
- SwissProt: P10997 Human
- Unigene: 46835 Human
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別名
- Amylin antibody
- DAP antibody
- Diabetes associated peptide antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab55411 は 1 報の論文で使用されています。
- Mescher T et al. Detection of varicella zoster virus antigen and DNA in two cases of cerebral amyloid angiopathy. J Neurol Sci 422:117315 (2021). PubMed: 33503519