Anti-Albumin 抗体 [EPSISR1] (ab137885)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPSISR1] to Albumin
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-Albumin antibody [EPSISR1]
Albumin 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPSISR1] to Albumin -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- WB: Human serum, liver and fetal liver lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPSISR1 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab137885の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/10000. Predicted molecular weight: 69 kDa.
For unpurified use at 1/1000 - 1/10000. |
特記事項 |
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WB
1/10000. Predicted molecular weight: 69 kDa. For unpurified use at 1/1000 - 1/10000. |
ターゲット情報
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機能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
組織特異性
Plasma. -
関連疾患
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
配列類似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻訳後修飾
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
- Unigene: 592379 Human
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製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
画像
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Anti-Albumin antibody [EPSISR1] (ab137885) at 1/10000 dilution (Purified) + Human liver lysate at 15 µg
Secondary
Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Predicted band size: 69 kDa
Observed band size: 68 kDa why is the actual band size different from the predicted?Blocking/Diluting buffer: 5% NFDM/TBST
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All lanes : Anti-Albumin antibody [EPSISR1] (ab137885) at 1/1000 dilution (unpurified)
Lane 1 : Human serum lysate
Lane 2 : Human fetal liver lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 69 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (9)
ab137885 は 9 報の論文で使用されています。
- Liu S et al. A method to measure the denatured proteins in the corona of nanoparticles based on the specific adsorption of Hsp90ab1. Nanoscale 12:15857-15868 (2020). PubMed: 32696774
- Scotland KB et al. Uropathogens Preferrentially Interact with Conditioning Film Components on the Surface of Indwelling Ureteral Stents Rather than Stent Material. Pathogens 9:N/A (2020). PubMed: 32962019
- Tysoe OC et al. Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue. Nat Protoc 14:1884-1925 (2019). PubMed: 31110298
- Yoshida M et al. Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice. Cell Metab 30:329-342.e5 (2019). PubMed: 31204283
- Costine-Bartell BA et al. Development of a Model of Hemispheric Hypodensity ("Big Black Brain"). J Neurotrauma 36:815-833 (2019). PubMed: 30039743
- Lin NC et al. Mesenchymal stem cells prolong survival and prevent lethal complications in a porcine model of fulminant liver failure. Xenotransplantation N/A:e12542 (2019). PubMed: 31219208
- Yu C et al. Scanningless and continuous 3D bioprinting of human tissues with decellularized extracellular matrix. Biomaterials 194:1-13 (2019). PubMed: 30562651
- Peng YC et al. Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity. Tumour Biol N/A:N/A (2016). Human . PubMed: 26886287
- Wang J et al. Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro. PLoS One 9:e85112 (2014). WB . PubMed: 24465489