Anti-Adiponectin Receptor 2/ADIPOR2 抗体 (ab223752)
Key features and details
- Rabbit polyclonal to Adiponectin Receptor 2/ADIPOR2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Adiponectin Receptor 2/ADIPOR2 antibody
Adiponectin Receptor 2/ADIPOR2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Adiponectin Receptor 2/ADIPOR2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human Adiponectin Receptor 2/ADIPOR2 aa 1-100.
Database link: Q86V24 -
ポジティブ・コントロール
- IHC-P: Human skeletal muscle, placenta, heart muscle and small intestine tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab223752の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. -
組織特異性
Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. -
配列類似性
Belongs to the ADIPOR family. -
ドメイン
The N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular. -
細胞内局在
Membrane. Localized to the cell membrane and intracellular organelles. - Information by UniProt
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参照データベース
- Entrez Gene: 79602 Human
- Omim: 607946 Human
- SwissProt: Q86V24 Human
- Unigene: 371642 Human
- Unigene: 708545 Human
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別名
- PAQR2 antibody
- ACDCR2 antibody
- Adiponectin receptor protein 2 antibody
see all
画像
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Paraffin-embedded human small intestine tissue stained for Adiponectin Receptor 2/ADIPOR2 using ab223752 at 1/20 dilution in immunohistochemical analysis.
Moderate cytoplasmic positivity in glandular cells.
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Paraffin-embedded human skeletal muscle tissue stained for Adiponectin Receptor 2/ADIPOR2 using ab223752 at 1/20 dilution in immunohistochemical analysis.
Moderate cytoplasmic positivity in myocytes.
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Paraffin-embedded human placenta tissue stained for Adiponectin Receptor 2/ADIPOR2 using ab223752 at 1/20 dilution in immunohistochemical analysis.
Strong cytoplasmic positivity in decidual cells.
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Paraffin-embedded human heart muscle tissue stained for Adiponectin Receptor 2/ADIPOR2 using ab223752 at 1/20 dilution in immunohistochemical analysis.
Moderate cytoplasmic positivity in cardiomyocytes.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab223752 は論文での使用が確認できていません。