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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Overview
Product name
Anti-MASH1/Achaete-scute homolog 1 antibody
MASH1/Achaete-scute homolog 1 抗体 (7件) 一覧
Description
Rabbit polyclonal to MASH1/Achaete-scute homolog 1
Tested applications
WB, ELISA, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Synthetic peptide (10-30 aa in length) at the C-term of last 50 aa of human Achaete-scute homolog 1 conjugated to KLH
Positive control
Human hepatocarcinoma tissues and mouse lung tissue lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
ab38556 was purified through a protein G column and eluted out with both high and low pH buffers and neutralised immediately after elution then followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Neurogenesis
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
Applications
Show applications key
Our Abpromise guarantee covers the use of ab38556 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/100 - 1/500.Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
ELISA
ELISA: 1/1000ELISA: 1/1000
IHC-P: Use at an assay dependent dilution.
Target
Function
May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Activates transcription by binding to the E box (5'-CANNTG-3').
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP50553
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Achaete scute complex homolog 1 antibody
- Achaete scute complex homolog like 1 antibody
- Achaete scute complex homologue 1 antibody
see all
Database links
- Entrez Gene: 429 Human
- Entrez Gene: 17172 Mouse
- Omim: 100790 Human
- SwissProt: P50553 Human
- SwissProt: Q02067 Mouse
- Unigene: 703025 Human
- Unigene: 712544 Human
- Unigene: 136217 Mouse
Anti-MASH1/Achaete-scute homolog 1 antibody images:
Western blot - Achaete-scute homolog 1 antibody (ab38556)
Anti-MASH1/Achaete-scute homolog 1 antibody (ab38556) at 1/500 dilution + Mouse lung tissue lysate
Predicted band size : 25 kDa
Observed band size : 25 kDa
Additional bands at : 15 kDa,28 kDa,45 kDa (possible dimer),55 kDa (possible dimer). We are unsure as to the identity of these extra bands.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Achaete-scute homolog 1 antibody (ab38556)
Formalin fixed and paraffin embedded human hepatocarcinoma tissue stained with ab38556, followed by AEC staining.
References for Anti-MASH1/Achaete-scute homolog 1 antibody (ab38556)
This product has been referenced in:
- Prajerova Iet al. Distinct effects of Sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro. Neuroscience : (2010). WB; Mouse.Read more (PubMed: 20868729) »
See 1 publication for this product
Publishing research using ab38556? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"