AS-041164, PI3K gamma inhibitor (ab120898)
Key features and details
- Potent and selective PI3Kγ inhibitor
- CAS Number: 6318-41-8
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
AS-041164, PI3K gamma inhibitor -
製品の詳細
Potent and selective PI3Kγ inhibitor -
生理活性の詳細
Potent PI3K inhibitor with selectivity for PI3Kγ (IC50 = 70 nM), compared to PI3Kα, β and δ (IC50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or no activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo. -
精製度
> 98% -
CAS 番号
6318-41-8 -
構造式
製品の特性
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体系名
5-[(1,3-Benzodioxol-5-yl)methylene]-2,4-thiazolidinedione
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分子量
249.24 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C(/C(S1)=C/C2=CC=C3C(OCO3)=C2)NC1=O -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab120898 は論文での使用が確認できていません。