Anti-APOBEC1 抗体 (ab80493)
Key features and details
- Goat polyclonal to APOBEC1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-APOBEC1 antibody -
製品の詳細
Goat polyclonal to APOBEC1 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Human, Orangutan -
免疫原
Synthetic peptide:
DVFYDPRELRKEAC
, corresponding to internal sequence amino acids 24-37 of Human APOBEC1 (NP_001635.2). -
ポジティブ・コントロール
- Mouse spleen lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 0.5% Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab80493 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab80493の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
特記事項 |
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WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. -
組織特異性
Expressed exclusively in the small intestine. -
配列類似性
Belongs to the cytidine and deoxycytidylate deaminase family. - Information by UniProt
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参照データベース
- Entrez Gene: 339 Human
- Entrez Gene: 11810 Mouse
- GenBank: L25877 Human
- GenBank: U21951 Mouse
- Omim: 600130 Human
- SwissProt: P41238 Human
- SwissProt: P51908 Mouse
- SwissProt: Q694B3 Orangutan
see all -
別名
- ABEC1_HUMAN antibody
- APOBEC 1 antibody
- APOBEC1 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab80493 は 1 報の論文で使用されています。
- Fossat N et al. C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47. EMBO Rep : (2014). PubMed: 24916387