製品の概要

  • 製品名
    AKT1 + PKN2 peptide substrate

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 配列
      KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC
    • 配列の追加情報
      The 39 amino acids of PDKtide peptide sequence is derived from two human proteins: residues 1-14 are based on AKT1 (307-320) and residues 16-39 are based on PKN2/PRK2 (961-984).

特性

Our Abpromise guarantee covers the use of ab204873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    HPLC

    Functional Studies

  • 備考

    ab204873 (AKT1 + PKN2 peptide substrate) can be utilized as a substrate for the following active protein kinases:

     

    ab126914 (Active human CDC7 + DBF4 full length protein)
    ab70320 (Active human CDK9+CyclinK full length protein)
    ab60834 (Active human PDPK1 full length protein)

     

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

関連情報

  • 細胞内局在
    AKT1: Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated form translocates to the nucleus. PKN2: Cytoplasm.

参考文献

ab204873 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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