Anti-AGE 抗体 (ab176173)
Key features and details
- Rabbit polyclonal to AGE
- Suitable for: WB
- Reacts with: Species independent
- Isotype: IgG
製品の概要
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製品名
Anti-AGE antibody
AGE 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to AGE -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Species independent -
免疫原
Full length native protein (purified) corresponding to AGE. Glycated ribonuclease (RNase) prepared by incubating RNase with glucose at 37C for several months.
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ポジティブ・コントロール
- Glycated ovalbumin, BSA and ribonuclease.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: 69% Tris glycine, 30% Glycerol
pH 7.4 - 7.8
Stabilizing proteins (0.5%) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab176173の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500.
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特記事項 |
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WB
1/500. |
ターゲット情報
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関連性
The non enzymatic reaction of reducing carbohydrates with lysine side chains and N terminal amino groups of macromolecules (amino acids, proteins, phospholipids and nucleic acids) is called the Maillard reaction or glycation. The latter products of this process, termed advanced glycation end products (AGEs), adversely affect the functional properties of proteins, lipids and DNA. In long lived tissue proteins, these chemical modifications accumulate with age and may contribute to the pathophysiology of ageing and long term complications of diabetes, atherosclerosis and renal failure. -
細胞内局在
Cell Membrane and Secreted -
別名
- Advanced glycation end products antibody
- AGEs antibody
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab176173 は 2 報の論文で使用されています。
- Liang Y et al. Inhibition of Caspase-1 Ameliorates Ischemia-Associated Blood-Brain Barrier Dysfunction and Integrity by Suppressing Pyroptosis Activation. Front Cell Neurosci 14:540669 (2020). PubMed: 33584203
- Shan G et al. Increase in Blood Glutathione and Erythrocyte Proteins Related to Glutathione Generation, Reduction and Utilization in African-American Old Women with Diabetes. J Sci Technol Environ 5:N/A (0). PubMed: 26770888