Anti-AFAP1L2 抗体 (ab106433)
Key features and details
- Rabbit polyclonal to AFAP1L2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-AFAP1L2 antibody -
製品の詳細
Rabbit polyclonal to AFAP1L2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
A 15 amino acid synthetic peptide near the C terminus of Human AFAP1L2 (NP_001001936).
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ポジティブ・コントロール
- WB: Mouse liver tissue lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106433の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 91 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 91 kDa. |
ターゲット情報
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機能
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. -
組織特異性
Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. -
配列類似性
Contains 2 PH domains. -
翻訳後修飾
Tyrosine phosphorylated (by SRC). -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 226250 Mouse
- SwissProt: Q5DTU0 Mouse
- Unigene: 226284 Mouse
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別名
- Actin filament-associated protein 1-like 2 antibody
- AF1L2_HUMAN antibody
- AFAP1-like protein 2 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab106433 は 3 報の論文で使用されています。
- Wang Q et al. XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells. Mol Carcinog 59:557-568 (2020). PubMed: 32159887
- Song K et al. Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels. Oncol Lett 20:68 (2020). PubMed: 32863901
- Shen J et al. XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelial-mesenchymal transition. Mol Med Rep 16:5592-5598 (2017). PubMed: 28849225