Anti-AC6 抗体 (ab14781)
Key features and details
- Rabbit polyclonal to AC6
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
-
製品名
Anti-AC6 antibody -
製品の詳細
Rabbit polyclonal to AC6 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Rat AC6 aa 1-100 (N terminal) conjugated to keyhole limpet haemocyanin.
Database link: Q03343 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.02% Sodium azide -
Concentration information loading...
-
精製度
Immunogen affinity purified -
特記事項(精製)
The affinity-purified antibodies are purified on antigen-sepharose affinity column and supplied in antibody stabilization buffer containing preservatives with low viscosity and cryogenic properties. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14781の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
1/500. Predicted molecular weight: 130 kDa.
|
特記事項 |
---|
WB
1/500. Predicted molecular weight: 130 kDa. |
ターゲット情報
-
機能
Membrane-bound, calcium-inhibitable adenylyl cyclase. -
配列類似性
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 112 Human
- Entrez Gene: 11512 Mouse
- Entrez Gene: 25289 Rat
- Omim: 600294 Human
- SwissProt: O43306 Human
- SwissProt: Q01341 Mouse
- SwissProt: Q03343 Rat
- Unigene: 525401 Human
see all -
別名
- AC6 antibody
- ACVI antibody
- ADCY 6 antibody
see all
データシートおよび資料
-
Datasheet download
参考文献 (6)
ab14781 は 6 報の論文で使用されています。
- Wu H et al. MiR-27a-3p binds to TET1 mediated DNA demethylation of ADCY6 regulates breast cancer progression via epithelial-mesenchymal transition. Front Oncol 12:957511 (2022). PubMed: 35978806
- Zhang X et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics 11:5650-5674 (2021). PubMed: 33897873
- Hampson E et al. P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells. Cells 10:N/A (2021). PubMed: 34572121
- Johnson GP et al. Mesenchymal stem cell mechanotransduction is cAMP dependent and regulated by adenylyl cyclase 6 and the primary cilium. J Cell Sci 131:N/A (2018). PubMed: 30301777
- Ikoma-Seki K et al. Role of LRP1 and ERK and cAMP Signaling Pathways in Lactoferrin-Induced Lipolysis in Mature Rat Adipocytes. PLoS One 10:e0141378 (2015). WB ; Rat . PubMed: 26506094
- Grünberger C et al. The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6. Circ Res 99:1197-206 (2006). WB ; Mouse . PubMed: 17068292