Anti-ACOT1 抗体 (ab100915)
Key features and details
- Rabbit polyclonal to ACOT1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ACOT1 antibody -
製品の詳細
Rabbit polyclonal to ACOT1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Recombinant fragment, corresponding to amino acids 183-421 of Human ACOT1 (BC132889).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute in 200µl sterile water -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab100915の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/1000 - 1/2000. Predicted molecular weight: 46 kDa.
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IHC-P |
1/100 - 1/500.
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特記事項 |
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WB
1/1000 - 1/2000. Predicted molecular weight: 46 kDa. |
IHC-P
1/100 - 1/500. |
ターゲット情報
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関連性
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. -
細胞内局在
Cytoplasmic -
参照データベース
- Entrez Gene: 641371 Human
- Entrez Gene: 26897 Mouse
- Omim: 614313 Human
- SwissProt: Q86TX2 Human
- SwissProt: O55137 Mouse
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別名
- ACH2 antibody
- Acyl CoA thioesterase 1, cytosolic antibody
- Acyl coenzyme A thioesterase 1 antibody
see all
画像
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All lanes : Anti-ACOT1 antibody (ab100915) at 1/1000 dilution
Lane 1 : Human Fetal Skin Lysate
Lane 2 : Human Fetal Liver Lysate
Lane 3 : Human Fetal Heart Lysate
Predicted band size: 46 kDa -
ab100915, at 1/100 dilution, staining cytoplasmic ACOT1 in formalin-fixed, paraffin-embedded Human fetal thymus tissue, by Immunohistochemistry.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab100915 は 4 報の論文で使用されています。
- Shadrach JL et al. Translatomic analysis of regenerating and degenerating spinal motor neurons in injury and ALS. iScience 24:102700 (2021). PubMed: 34235408
- Liu Y et al. Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition. Cell Death Dis 11:756 (2020). PubMed: 32934217
- Simsek D et al. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell 169:1051-1065.e18 (2017). PubMed: 28575669
- Jeckel KM et al. Dietary fatty acids alter left ventricular myocardial gene expression in Wistar rats. Nutr Res 34:694-706 (2014). WB ; Rat . PubMed: 25172377